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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKB All Species: 23.33
Human Site: S735 Identified Species: 51.33
UniProt: Q9Y6T7 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6T7 NP_004071.1 804 90595 S735 Q I Y T G L K S A G R R L A Q
Chimpanzee Pan troglodytes XP_001148960 804 90603 S735 Q I Y T G L K S A G R R L A Q
Rhesus Macaque Macaca mulatta XP_001105384 789 88608 S720 Q I Y T G L K S A G R R L A Q
Dog Lupus familis XP_539445 886 99592 S817 Q I Y T G L K S A G R R L A Q
Cat Felis silvestris
Mouse Mus musculus Q6NS52 802 90253 S733 Q I Y T G L K S A G R R L A Q
Rat Rattus norvegicus P49621 801 90269 S732 Q I Y T G L K S A G R R L A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511802 697 78726 T629 V E T L Q E T T V M T P E N R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q01583 1211 132942 C1136 E V I G L E N C L H M G Q V R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q03603 812 91362 R726 G Q I K A G V R G A R R L S Q
Sea Urchin Strong. purpuratus XP_001197889 1217 132437 R1149 N I D L M F A R Q S I G D K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39017 728 79965 I660 C A P L P V Q I D G E P W N Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 96.6 88.2 N.A. 96.5 96.1 N.A. 72.2 N.A. N.A. N.A. N.A. 34.9 N.A. 52 42.4
Protein Similarity: 100 99.8 97.5 89.5 N.A. 98.1 97.8 N.A. 78.2 N.A. N.A. N.A. N.A. 47.5 N.A. 66.1 52.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 N.A. N.A. N.A. N.A. 0 N.A. 26.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 N.A. N.A. N.A. N.A. 20 N.A. 33.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 23.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 10 0 55 10 0 0 0 55 0 % A
% Cys: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 10 0 0 0 10 0 0 % D
% Glu: 10 10 0 0 0 19 0 0 0 0 10 0 10 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 10 55 10 0 0 10 64 0 19 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 64 19 0 0 0 0 10 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 55 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 28 10 55 0 0 10 0 0 0 64 0 10 % L
% Met: 0 0 0 0 10 0 0 0 0 10 10 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 10 0 0 0 0 0 0 19 0 % N
% Pro: 0 0 10 0 10 0 0 0 0 0 0 19 0 0 0 % P
% Gln: 55 10 0 0 10 0 10 0 10 0 0 0 10 0 73 % Q
% Arg: 0 0 0 0 0 0 0 19 0 0 64 64 0 0 19 % R
% Ser: 0 0 0 0 0 0 0 55 0 10 0 0 0 10 0 % S
% Thr: 0 0 10 55 0 0 10 10 0 0 10 0 0 0 0 % T
% Val: 10 10 0 0 0 10 10 0 10 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 55 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _