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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKB
All Species:
19.7
Human Site:
S394
Identified Species:
43.33
UniProt:
Q9Y6T7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6T7
NP_004071.1
804
90595
S394
S
V
P
E
E
R
Q
S
T
V
K
K
E
K
S
Chimpanzee
Pan troglodytes
XP_001148960
804
90603
S394
S
V
P
E
E
R
Q
S
T
V
K
K
E
K
S
Rhesus Macaque
Macaca mulatta
XP_001105384
789
88608
S379
S
V
P
E
E
R
Q
S
T
V
K
K
E
K
S
Dog
Lupus familis
XP_539445
886
99592
A476
S
V
P
E
E
R
Q
A
T
V
K
K
E
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6NS52
802
90253
S392
S
V
P
E
E
R
Q
S
T
A
K
K
E
K
S
Rat
Rattus norvegicus
P49621
801
90269
S391
S
V
P
E
E
R
Q
S
T
A
K
K
E
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511802
697
78726
G331
A
N
S
V
T
V
D
G
Q
G
L
Q
I
T
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
K530
S
V
N
Q
A
H
K
K
S
Q
M
H
H
H
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
N407
S
T
S
L
K
N
H
N
F
S
S
H
S
A
S
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
S823
N
H
G
S
N
R
R
S
T
L
T
P
K
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
L362
L
P
S
D
A
R
P
L
L
V
F
I
N
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
96.6
88.2
N.A.
96.5
96.1
N.A.
72.2
N.A.
N.A.
N.A.
N.A.
34.9
N.A.
52
42.4
Protein Similarity:
100
99.8
97.5
89.5
N.A.
98.1
97.8
N.A.
78.2
N.A.
N.A.
N.A.
N.A.
47.5
N.A.
66.1
52.6
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
13.3
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
19
0
0
10
0
19
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
55
55
0
0
0
0
0
0
0
55
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
10
0
10
0
0
0
0
19
% G
% His:
0
10
0
0
0
10
10
0
0
0
0
19
10
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% I
% Lys:
0
0
0
0
10
0
10
10
0
0
55
55
10
64
10
% K
% Leu:
10
0
0
10
0
0
0
10
10
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
10
10
10
0
10
10
0
10
0
0
0
0
10
0
0
% N
% Pro:
0
10
55
0
0
0
10
0
0
0
0
10
0
0
10
% P
% Gln:
0
0
0
10
0
0
55
0
10
10
0
10
0
0
10
% Q
% Arg:
0
0
0
0
0
73
10
0
0
0
0
0
0
0
0
% R
% Ser:
73
0
28
10
0
0
0
55
10
10
10
0
10
0
55
% S
% Thr:
0
10
0
0
10
0
0
0
64
0
10
0
0
10
0
% T
% Val:
0
64
0
10
0
10
0
0
0
46
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _