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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKB
All Species:
13.03
Human Site:
S143
Identified Species:
28.67
UniProt:
Q9Y6T7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6T7
NP_004071.1
804
90595
S143
K
D
I
V
C
Y
L
S
L
L
E
R
G
R
P
Chimpanzee
Pan troglodytes
XP_001148960
804
90603
S143
K
D
I
V
C
Y
L
S
L
L
E
R
G
R
P
Rhesus Macaque
Macaca mulatta
XP_001105384
789
88608
E140
G
R
P
E
D
K
L
E
F
M
F
R
L
Y
D
Dog
Lupus familis
XP_539445
886
99592
L226
D
I
V
C
Y
L
S
L
L
E
R
G
R
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6NS52
802
90253
L143
D
I
V
C
Y
L
S
L
L
E
R
G
R
P
E
Rat
Rattus norvegicus
P49621
801
90269
L143
D
I
V
C
Y
L
S
L
L
E
R
G
R
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511802
697
78726
H107
T
E
L
S
P
I
L
H
E
M
M
E
E
I
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
S280
K
D
V
V
C
Y
L
S
L
L
E
A
G
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
D148
G
P
R
V
A
N
N
D
S
Q
E
P
R
I
P
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
S572
K
D
I
V
C
Y
L
S
L
L
E
G
G
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
K138
S
S
A
P
K
D
C
K
C
V
S
M
V
G
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
96.6
88.2
N.A.
96.5
96.1
N.A.
72.2
N.A.
N.A.
N.A.
N.A.
34.9
N.A.
52
42.4
Protein Similarity:
100
99.8
97.5
89.5
N.A.
98.1
97.8
N.A.
78.2
N.A.
N.A.
N.A.
N.A.
47.5
N.A.
66.1
52.6
P-Site Identity:
100
100
13.3
6.6
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
20
86.6
P-Site Similarity:
100
100
20
13.3
N.A.
13.3
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
28
37
0
10
0
10
0
0
0
0
0
0
% C
% Asp:
28
37
0
0
10
10
0
10
0
0
0
0
0
0
19
% D
% Glu:
0
10
0
10
0
0
0
10
10
28
46
10
10
0
28
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% F
% Gly:
19
0
0
0
0
0
0
0
0
0
0
37
37
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
28
28
0
0
10
0
0
0
0
0
0
0
19
0
% I
% Lys:
37
0
0
0
10
10
0
10
0
0
0
0
0
10
0
% K
% Leu:
0
0
10
0
0
28
55
28
64
37
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
19
10
10
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
10
10
0
0
0
0
0
0
10
0
28
46
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
10
10
0
0
0
0
0
0
0
28
28
37
28
0
% R
% Ser:
10
10
0
10
0
0
28
37
10
0
10
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
37
46
0
0
0
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
28
37
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _