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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNFRSF11A All Species: 8.18
Human Site: Y349 Identified Species: 20
UniProt: Q9Y6Q6 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6Q6 NP_003830.1 616 66034 Y349 Q M P T E D E Y M D R P S Q P
Chimpanzee Pan troglodytes XP_523949 617 66149 Y349 Q M P M E D E Y M D R P F Q P
Rhesus Macaque Macaca mulatta XP_001104333 278 30816 Y31 T A C R E K Q Y L I N S Q C C
Dog Lupus familis XP_541077 629 66314 D345 P T E D E Y V D R S S Q T P D
Cat Felis silvestris
Mouse Mus musculus O35305 625 66603 Q351 E Y T D R P S Q P S T G S L L
Rat Rattus norvegicus XP_573424 633 67589 Q351 E Y T D R P S Q P P N G S L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514545 485 51078 S238 W E P D T D S S S D S F I S T
Chicken Gallus gallus XP_001233219 655 70250 Y348 K D L N T A D Y L P L L S Q P
Frog Xenopus laevis NP_001086287 387 44550 V140 G T P E S D T V C R P C P E G
Zebra Danio Brachydanio rerio XP_002666674 574 62653 C326 S P L S G S S C S C A P K E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.7 20.6 70.4 N.A. 67.1 67.1 N.A. 40 45 20.4 26.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.6 29.7 76.9 N.A. 75 74.7 N.A. 50 57.4 33.5 39.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 13.3 6.6 N.A. 6.6 6.6 N.A. 20 26.6 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 26.6 13.3 N.A. 13.3 13.3 N.A. 20 46.6 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 10 10 10 0 10 0 10 10 % C
% Asp: 0 10 0 40 0 40 10 10 0 30 0 0 0 0 10 % D
% Glu: 20 10 10 10 40 0 20 0 0 0 0 0 0 20 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 10 % F
% Gly: 10 0 0 0 10 0 0 0 0 0 0 20 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % I
% Lys: 10 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 20 0 0 0 0 0 20 0 10 10 0 20 10 % L
% Met: 0 20 0 10 0 0 0 0 20 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 20 0 0 0 0 % N
% Pro: 10 10 40 0 0 20 0 0 20 20 10 30 10 10 40 % P
% Gln: 20 0 0 0 0 0 10 20 0 0 0 10 10 30 0 % Q
% Arg: 0 0 0 10 20 0 0 0 10 10 20 0 0 0 0 % R
% Ser: 10 0 0 10 10 10 40 10 20 20 20 10 40 10 0 % S
% Thr: 10 20 20 10 20 0 10 0 0 0 10 0 10 0 10 % T
% Val: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 20 0 0 0 10 0 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _