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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1M2
All Species:
26.22
Human Site:
Y418
Identified Species:
57.69
UniProt:
Q9Y6Q5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6Q5
NP_005489.2
423
48108
Y418
Y
I
T
Q
S
G
D
Y
Q
L
R
T
S
_
_
Chimpanzee
Pan troglodytes
XP_001165482
423
48062
Y418
Y
I
T
Q
S
G
D
Y
Q
L
R
T
S
_
_
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853941
421
47786
Y416
Y
I
T
Q
S
G
D
Y
Q
L
R
T
S
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVP1
423
48118
Y418
Y
I
T
Q
S
G
D
Y
Q
L
R
T
S
_
_
Rat
Rattus norvegicus
Q32Q06
423
48538
Y418
Y
I
T
Q
N
G
D
Y
Q
L
R
T
Q
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMP6
433
49371
Frog
Xenopus laevis
Q801Q8
435
49666
Zebra Danio
Brachydanio rerio
Q7ZW98
436
49724
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649906
426
48922
Y421
Y
I
T
Q
N
G
D
Y
Q
L
R
T
N
_
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35602
422
48210
Y417
Y
I
T
Q
N
G
E
Y
E
M
R
M
K
_
_
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
D468
R
Y
I
T
Q
S
G
D
D
Y
T
I
R
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
95
N.A.
96.9
79.6
N.A.
N.A.
39.4
39
38.7
N.A.
75.3
N.A.
69.7
N.A.
Protein Similarity:
100
100
N.A.
96.9
N.A.
98.8
91.9
N.A.
N.A.
63.2
62.7
62.8
N.A.
88.9
N.A.
86.2
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
84.6
N.A.
N.A.
0
0
0
N.A.
84.6
N.A.
53.8
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
92.3
N.A.
N.A.
0
0
0
N.A.
100
N.A.
84.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
69.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
55
10
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
64
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
64
10
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
55
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% M
% Asn:
0
0
0
0
28
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
64
10
0
0
0
55
0
0
0
10
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
64
0
10
0
0
% R
% Ser:
0
0
0
0
37
10
0
0
0
0
0
0
37
0
0
% S
% Thr:
0
0
64
10
0
0
0
0
0
0
10
55
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
64
10
0
0
0
0
0
64
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
64
% _