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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1M2
All Species:
19.39
Human Site:
Y21
Identified Species:
42.67
UniProt:
Q9Y6Q5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6Q5
NP_005489.2
423
48108
Y21
K
P
L
I
S
R
N
Y
K
G
D
V
A
M
S
Chimpanzee
Pan troglodytes
XP_001165482
423
48062
Y21
K
P
L
I
S
R
N
Y
K
G
D
V
A
M
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853941
421
47786
E27
K
G
D
V
A
M
S
E
I
E
H
F
M
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVP1
423
48118
Y21
K
P
L
I
S
R
N
Y
K
G
D
V
P
M
T
Rat
Rattus norvegicus
Q32Q06
423
48538
Y21
K
V
L
I
C
R
N
Y
R
G
D
V
D
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMP6
433
49371
I24
S
R
V
Y
R
D
D
I
G
R
N
A
V
D
A
Frog
Xenopus laevis
Q801Q8
435
49666
I24
S
R
V
Y
R
D
D
I
G
R
N
A
V
D
A
Zebra Danio
Brachydanio rerio
Q7ZW98
436
49724
I24
S
R
V
Y
R
D
D
I
G
R
N
A
V
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649906
426
48922
Y21
K
V
L
I
S
R
N
Y
R
G
D
N
I
D
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35602
422
48210
Y21
K
T
I
I
S
R
N
Y
R
G
D
I
D
M
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
D30
D
I
P
L
S
A
I
D
K
F
P
I
L
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
95
N.A.
96.9
79.6
N.A.
N.A.
39.4
39
38.7
N.A.
75.3
N.A.
69.7
N.A.
Protein Similarity:
100
100
N.A.
96.9
N.A.
98.8
91.9
N.A.
N.A.
63.2
62.7
62.8
N.A.
88.9
N.A.
86.2
N.A.
P-Site Identity:
100
100
N.A.
6.6
N.A.
86.6
73.3
N.A.
N.A.
0
0
0
N.A.
60
N.A.
60
N.A.
P-Site Similarity:
100
100
N.A.
26.6
N.A.
93.3
80
N.A.
N.A.
26.6
26.6
26.6
N.A.
66.6
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
69.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
0
0
0
28
19
0
28
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
28
28
10
0
0
55
0
19
37
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
28
55
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
10
10
55
0
0
10
28
10
0
0
19
10
0
0
% I
% Lys:
64
0
0
0
0
0
0
0
37
0
0
0
0
0
0
% K
% Leu:
0
0
46
10
0
0
0
0
0
0
0
0
10
10
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
10
46
10
% M
% Asn:
0
0
0
0
0
0
55
0
0
0
28
10
0
0
0
% N
% Pro:
0
28
10
0
0
0
0
0
0
0
10
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
28
0
0
28
55
0
0
28
28
0
0
0
0
0
% R
% Ser:
28
0
0
0
55
0
10
0
0
0
0
0
0
0
37
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
19
% T
% Val:
0
19
28
10
0
0
0
0
0
0
0
37
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
28
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _