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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1M2
All Species:
25.45
Human Site:
Y134
Identified Species:
56
UniProt:
Q9Y6Q5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6Q5
NP_005489.2
423
48108
Y134
D
S
K
I
L
Q
E
Y
I
T
Q
Q
S
N
K
Chimpanzee
Pan troglodytes
XP_001165482
423
48062
Y134
D
S
K
I
L
Q
E
Y
I
T
Q
Q
S
N
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853941
421
47786
Y132
D
S
K
I
L
Q
E
Y
I
T
Q
Q
G
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVP1
423
48118
Y134
D
S
K
I
L
Q
E
Y
I
T
Q
Q
G
N
K
Rat
Rattus norvegicus
Q32Q06
423
48538
Y134
D
S
K
I
L
Q
E
Y
I
T
Q
E
G
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMP6
433
49371
F132
E
T
G
A
L
K
T
F
I
T
Q
Q
G
I
K
Frog
Xenopus laevis
Q801Q8
435
49666
F132
E
T
G
A
L
K
T
F
I
T
Q
Q
G
I
K
Zebra Danio
Brachydanio rerio
Q7ZW98
436
49724
F132
E
T
G
A
L
K
T
F
I
T
Q
Q
G
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649906
426
48922
E136
T
D
S
K
I
L
Q
E
Y
I
T
Q
E
G
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35602
422
48210
Y134
E
S
R
I
L
Q
E
Y
I
T
Q
E
G
Q
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
Y135
E
T
K
M
L
K
Q
Y
I
T
Q
K
S
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
95
N.A.
96.9
79.6
N.A.
N.A.
39.4
39
38.7
N.A.
75.3
N.A.
69.7
N.A.
Protein Similarity:
100
100
N.A.
96.9
N.A.
98.8
91.9
N.A.
N.A.
63.2
62.7
62.8
N.A.
88.9
N.A.
86.2
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
80
N.A.
N.A.
40
40
40
N.A.
6.6
N.A.
66.6
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
66.6
66.6
N.A.
20
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
69.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
46
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
46
0
0
0
0
0
55
10
0
0
0
19
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
28
0
0
0
0
0
10
0
% F
% Gly:
0
0
28
0
0
0
0
0
0
0
0
0
64
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
0
55
10
0
0
0
91
10
0
0
0
28
0
% I
% Lys:
0
0
55
10
0
37
0
0
0
0
0
10
0
0
91
% K
% Leu:
0
0
0
0
91
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
37
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
55
19
0
0
0
91
73
0
10
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
55
10
0
0
0
0
0
0
0
0
0
28
0
0
% S
% Thr:
10
37
0
0
0
0
28
0
0
91
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _