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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STON1 All Species: 14.85
Human Site: S220 Identified Species: 32.67
UniProt: Q9Y6Q2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6Q2 NP_006864.2 735 83141 S220 E M P I D Q K S L N K C S L N
Chimpanzee Pan troglodytes XP_001151548 1157 129181 S220 E M P I D Q K S L N K C S L N
Rhesus Macaque Macaca mulatta XP_001105584 896 100013 S372 D A I S F D D S S K T Q S H S
Dog Lupus familis XP_864856 735 82747 S219 D M P V D Q K S L N Q C S L N
Cat Felis silvestris
Mouse Mus musculus Q8CDJ8 730 81774 S215 E V P I G H K S L T Q C S L D
Rat Rattus norvegicus NP_001129346 895 99472 S369 D A I S F D D S G K S Q S H P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505629 865 95494 D289 L P K V K K L D I S S L T R P
Chicken Gallus gallus XP_419372 1194 133022 K216 K E I C H D Q K S L N Q G S F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028915 859 96510 K336 Q K D S A I E K D S V Q S S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396872 1188 129859 E296 N P F V S I T E Q Q A S P V Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795059 1041 114812 A430 Q V I F A A A A A A Q Q S A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.6 32.3 88 N.A. 76.7 32.7 N.A. 30.7 41.2 N.A. 30.1 N.A. N.A. 21.7 N.A. 23.2
Protein Similarity: 100 63.1 49.7 92.5 N.A. 84.9 49.1 N.A. 49.3 48.2 N.A. 48.8 N.A. N.A. 34.6 N.A. 39.1
P-Site Identity: 100 100 13.3 80 N.A. 60 13.3 N.A. 0 0 N.A. 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 26.6 100 N.A. 80 20 N.A. 33.3 13.3 N.A. 26.6 N.A. N.A. 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 0 19 10 10 10 10 10 10 0 0 10 10 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 37 0 0 0 % C
% Asp: 28 0 10 0 28 28 19 10 10 0 0 0 0 0 10 % D
% Glu: 28 10 0 0 0 0 10 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 10 19 0 0 0 0 0 0 0 0 0 19 % F
% Gly: 0 0 0 0 10 0 0 0 10 0 0 0 10 0 0 % G
% His: 0 0 0 0 10 10 0 0 0 0 0 0 0 19 0 % H
% Ile: 0 0 37 28 0 19 0 0 10 0 0 0 0 0 0 % I
% Lys: 10 10 10 0 10 10 37 19 0 19 19 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 10 0 37 10 0 10 0 37 0 % L
% Met: 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 28 10 0 0 0 28 % N
% Pro: 0 19 37 0 0 0 0 0 0 0 0 0 10 0 19 % P
% Gln: 19 0 0 0 0 28 10 0 10 10 28 46 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 28 10 0 0 55 19 19 19 10 73 19 10 % S
% Thr: 0 0 0 0 0 0 10 0 0 10 10 0 10 0 0 % T
% Val: 0 19 0 28 0 0 0 0 0 0 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _