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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STON1 All Species: 11.82
Human Site: S121 Identified Species: 26
UniProt: Q9Y6Q2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6Q2 NP_006864.2 735 83141 S121 L A I S G G E S S L L P T R P
Chimpanzee Pan troglodytes XP_001151548 1157 129181 S121 L A I S G G E S S L L P T R P
Rhesus Macaque Macaca mulatta XP_001105584 896 100013 L173 C S Y T D L Q L I N A E E Q T
Dog Lupus familis XP_864856 735 82747 S121 L T T S G G G S S L L P T K S
Cat Felis silvestris
Mouse Mus musculus Q8CDJ8 730 81774 S110 Y P I P E C S S S S A P T T A
Rat Rattus norvegicus NP_001129346 895 99472 L170 P S Y T D L Q L I N A E E Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505629 865 95494 S164 S P S I G P S S T D M R S T N
Chicken Gallus gallus XP_419372 1194 133022 A117 P G V C S S L A S Q K P S S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028915 859 96510 S144 S C P H S P N S S L C Q D D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396872 1188 129859 D185 L S V T G A M D A T S N H L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795059 1041 114812 N293 I H M S D H A N D L E V S R F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.6 32.3 88 N.A. 76.7 32.7 N.A. 30.7 41.2 N.A. 30.1 N.A. N.A. 21.7 N.A. 23.2
Protein Similarity: 100 63.1 49.7 92.5 N.A. 84.9 49.1 N.A. 49.3 48.2 N.A. 48.8 N.A. N.A. 34.6 N.A. 39.1
P-Site Identity: 100 100 0 66.6 N.A. 33.3 0 N.A. 13.3 13.3 N.A. 20 N.A. N.A. 13.3 N.A. 20
P-Site Similarity: 100 100 26.6 73.3 N.A. 33.3 26.6 N.A. 33.3 33.3 N.A. 20 N.A. N.A. 40 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 0 0 10 10 10 10 0 28 0 0 0 19 % A
% Cys: 10 10 0 10 0 10 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 28 0 0 10 10 10 0 0 10 10 0 % D
% Glu: 0 0 0 0 10 0 19 0 0 0 10 19 19 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 10 0 0 46 28 10 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 10 0 10 0 0 0 0 0 0 10 0 0 % H
% Ile: 10 0 28 10 0 0 0 0 19 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % K
% Leu: 37 0 0 0 0 19 10 19 0 46 28 0 0 10 19 % L
% Met: 0 0 10 0 0 0 10 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 10 0 19 0 10 0 0 10 % N
% Pro: 19 19 10 10 0 19 0 0 0 0 0 46 0 0 19 % P
% Gln: 0 0 0 0 0 0 19 0 0 10 0 10 0 19 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 28 0 % R
% Ser: 19 28 10 37 19 10 19 55 55 10 10 0 28 10 10 % S
% Thr: 0 10 10 28 0 0 0 0 10 10 0 0 37 19 10 % T
% Val: 0 0 19 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _