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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STON1 All Species: 14.55
Human Site: S117 Identified Species: 32
UniProt: Q9Y6Q2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6Q2 NP_006864.2 735 83141 S117 S D S P L A I S G G E S S L L
Chimpanzee Pan troglodytes XP_001151548 1157 129181 S117 S D S P L A I S G G E S S L L
Rhesus Macaque Macaca mulatta XP_001105584 896 100013 T169 P S F G C S Y T D L Q L I N A
Dog Lupus familis XP_864856 735 82747 S117 S N S P L T T S G G G S S L L
Cat Felis silvestris
Mouse Mus musculus Q8CDJ8 730 81774 P106 T H V L Y P I P E C S S S S A
Rat Rattus norvegicus NP_001129346 895 99472 T166 P S V A P S Y T D L Q L I N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505629 865 95494 I160 E D T G S P S I G P S S T D M
Chicken Gallus gallus XP_419372 1194 133022 C113 N L P S P G V C S S L A S Q K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028915 859 96510 H140 S H S P S C P H S P N S S L C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396872 1188 129859 T181 K D L I L S V T G A M D A T S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795059 1041 114812 S289 S S T P I H M S D H A N D L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.6 32.3 88 N.A. 76.7 32.7 N.A. 30.7 41.2 N.A. 30.1 N.A. N.A. 21.7 N.A. 23.2
Protein Similarity: 100 63.1 49.7 92.5 N.A. 84.9 49.1 N.A. 49.3 48.2 N.A. 48.8 N.A. N.A. 34.6 N.A. 39.1
P-Site Identity: 100 100 0 73.3 N.A. 20 0 N.A. 20 6.6 N.A. 40 N.A. N.A. 20 N.A. 26.6
P-Site Similarity: 100 100 20 80 N.A. 26.6 20 N.A. 40 26.6 N.A. 40 N.A. N.A. 46.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 19 0 0 0 10 10 10 10 0 28 % A
% Cys: 0 0 0 0 10 10 0 10 0 10 0 0 0 0 10 % C
% Asp: 0 37 0 0 0 0 0 0 28 0 0 10 10 10 0 % D
% Glu: 10 0 0 0 0 0 0 0 10 0 19 0 0 0 10 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 19 0 10 0 0 46 28 10 0 0 0 0 % G
% His: 0 19 0 0 0 10 0 10 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 10 10 0 28 10 0 0 0 0 19 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 10 10 10 37 0 0 0 0 19 10 19 0 46 28 % L
% Met: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 10 % M
% Asn: 10 10 0 0 0 0 0 0 0 0 10 10 0 19 0 % N
% Pro: 19 0 10 46 19 19 10 10 0 19 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 19 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 46 28 37 10 19 28 10 37 19 10 19 55 55 10 10 % S
% Thr: 10 0 19 0 0 10 10 28 0 0 0 0 10 10 0 % T
% Val: 0 0 19 0 0 0 19 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 19 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _