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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP3
All Species:
11.52
Human Site:
S447
Identified Species:
19.49
UniProt:
Q9Y6I4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6I4
NP_006528.2
520
58897
S447
Y
L
L
E
P
E
N
S
G
P
E
S
C
L
Y
Chimpanzee
Pan troglodytes
XP_510466
498
56646
G426
L
L
E
P
E
N
S
G
P
E
S
C
L
Y
D
Rhesus Macaque
Macaca mulatta
XP_001105997
520
58882
S447
Y
L
L
E
P
E
N
S
G
P
E
S
C
L
Y
Dog
Lupus familis
XP_544715
435
49586
G363
L
L
E
P
E
N
S
G
P
E
H
C
L
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91W36
520
58850
S447
Y
L
L
E
P
E
N
S
G
P
D
S
C
L
Y
Rat
Rattus norvegicus
B2GUX4
565
62681
F492
Q
R
L
S
L
G
D
F
A
S
D
K
V
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O57429
357
40913
S285
L
D
L
R
E
F
A
S
Q
S
C
N
H
A
V
Frog
Xenopus laevis
Q6DCJ1
523
60090
R443
M
A
S
S
K
E
S
R
M
N
G
Q
Y
Q
Q
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
P434
M
N
G
Q
Y
Q
Q
P
V
D
S
L
N
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR1
735
82440
E663
D
M
T
P
F
M
S
E
K
K
N
A
Y
G
D
Honey Bee
Apis mellifera
XP_392160
541
61414
G469
G
V
N
G
T
K
L
G
A
S
N
S
H
L
Y
Nematode Worm
Caenorhab. elegans
NP_493434
699
79496
T623
P
M
G
Q
L
D
V
T
Q
F
L
T
D
D
S
Sea Urchin
Strong. purpuratus
XP_781718
499
56662
A427
T
T
V
Y
D
L
A
A
V
I
V
H
Q
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50102
471
53605
K399
C
S
T
K
E
K
D
K
H
S
E
N
G
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
99.2
82.3
N.A.
96.5
26
N.A.
N.A.
27.6
27.7
27.8
N.A.
22.9
41.5
23.4
53.4
Protein Similarity:
100
95
99.6
83
N.A.
98.8
39.2
N.A.
N.A.
41.3
43.2
44
N.A.
39.8
58.2
36.4
69
P-Site Identity:
100
6.6
100
6.6
N.A.
93.3
6.6
N.A.
N.A.
13.3
6.6
0
N.A.
0
20
0
0
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
20
N.A.
N.A.
20
13.3
13.3
N.A.
20
33.3
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
15
8
15
0
0
8
0
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
8
15
22
0
0
% C
% Asp:
8
8
0
0
8
8
15
0
0
8
15
0
8
8
29
% D
% Glu:
0
0
15
22
29
29
0
8
0
15
22
0
0
0
0
% E
% Phe:
0
0
0
0
8
8
0
8
0
8
0
0
0
0
0
% F
% Gly:
8
0
15
8
0
8
0
22
22
0
8
0
8
22
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
8
15
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
8
8
15
0
8
8
8
0
8
0
8
0
% K
% Leu:
22
36
36
0
15
8
8
0
0
0
8
8
15
29
0
% L
% Met:
15
15
0
0
0
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
15
22
0
0
8
15
15
8
8
0
% N
% Pro:
8
0
0
22
22
0
0
8
15
22
0
0
0
0
0
% P
% Gln:
8
0
0
15
0
8
8
0
15
0
0
8
8
8
8
% Q
% Arg:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
15
0
0
29
29
0
29
15
29
0
0
22
% S
% Thr:
8
8
15
0
8
0
0
8
0
0
0
8
0
0
0
% T
% Val:
0
8
8
0
0
0
8
0
15
0
8
0
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
22
0
0
8
8
0
0
0
0
0
0
0
15
15
29
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _