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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BZW2
All Species:
30.91
Human Site:
Y278
Identified Species:
56.67
UniProt:
Q9Y6E2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6E2
NP_001153239.1
419
48162
Y278
P
I
K
E
V
V
L
Y
V
K
E
E
M
K
R
Chimpanzee
Pan troglodytes
XP_518982
477
54244
Y336
P
I
K
E
V
V
L
Y
V
K
E
E
M
K
R
Rhesus Macaque
Macaca mulatta
XP_001104484
580
65864
Y439
P
I
K
E
V
V
L
Y
V
K
E
E
M
K
R
Dog
Lupus familis
XP_862408
378
43352
K256
Q
Q
S
L
G
T
R
K
E
L
Q
K
E
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91VK1
419
48045
Y278
P
I
K
E
V
V
L
Y
V
K
E
E
M
K
R
Rat
Rattus norvegicus
Q9WTT7
419
48031
Y278
P
I
K
E
V
V
L
Y
V
K
E
E
M
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505311
421
48348
V298
L
K
E
L
S
E
Y
V
R
N
Q
Q
T
I
G
Chicken
Gallus gallus
Q5ZL42
414
47824
Y278
P
I
K
E
M
V
L
Y
V
K
E
E
M
K
R
Frog
Xenopus laevis
Q8AVM7
419
48119
Y277
A
H
K
E
I
S
V
Y
V
K
D
E
M
K
K
Zebra Danio
Brachydanio rerio
Q1LUC1
421
48306
Y280
P
I
R
E
I
V
V
Y
V
K
E
E
M
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNE2
422
49206
D278
P
Y
N
E
I
T
S
D
I
K
D
F
S
Q
R
Honey Bee
Apis mellifera
XP_395256
420
48465
D279
P
L
K
D
I
I
L
D
L
K
E
M
A
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32501
712
81143
G473
I
V
G
D
K
G
V
G
Y
I
Y
E
S
E
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
71.2
90.2
N.A.
99
98.8
N.A.
55.3
92.3
71.1
84.3
N.A.
50
52.3
N.A.
N.A.
Protein Similarity:
100
87.4
71.9
90.2
N.A.
99.5
99.5
N.A.
70.5
95.6
87.5
94.5
N.A.
72.7
73.5
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
93.3
53.3
73.3
N.A.
26.6
33.3
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
20
100
80
100
N.A.
53.3
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
0
0
0
16
0
0
16
0
0
0
0
% D
% Glu:
0
0
8
70
0
8
0
0
8
0
62
70
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
8
0
8
8
0
8
0
0
0
0
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
54
0
0
31
8
0
0
8
8
0
0
0
8
0
% I
% Lys:
0
8
62
0
8
0
0
8
0
77
0
8
0
62
24
% K
% Leu:
8
8
0
16
0
0
54
0
8
8
0
0
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
62
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
0
16
8
0
16
8
% Q
% Arg:
0
0
8
0
0
0
8
0
8
0
0
0
0
0
54
% R
% Ser:
0
0
8
0
8
8
8
0
0
0
0
0
16
0
0
% S
% Thr:
0
0
0
0
0
16
0
0
0
0
0
0
8
0
0
% T
% Val:
0
8
0
0
39
54
24
8
62
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
62
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _