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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AUP1 All Species: 1.82
Human Site: S424 Identified Species: 3.64
UniProt: Q9Y679 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.45
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y679 NP_853553.1 476 53028 S424 S L P T A S A S K F P S S G P
Chimpanzee Pan troglodytes XP_001161094 410 45740 K359 L P T A S A S K F P S S G P V
Rhesus Macaque Macaca mulatta XP_001110957 410 45712 K359 L P T A S A P K F P S S G P V
Dog Lupus familis XP_852590 410 45740 K359 L P T A S A P K F P S S G P V
Cat Felis silvestris
Mouse Mus musculus P70295 410 46103 K359 P P A P S A P K F P S S G L A
Rat Rattus norvegicus A1L134 410 46181 K359 L P T A S A P K F P S S G L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232437 481 51725 G426 S W A A S A S G I Q G S V A L
Frog Xenopus laevis B1H1N7 399 44798 V347 E G T S K S R V S R P L P Q G
Zebra Danio Brachydanio rerio Q6PBN5 423 47395 M372 A S S T P S A M V S S P N L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392941 392 44951 Q341 T Y T P D S S Q T I M R S A P
Nematode Worm Caenorhab. elegans P34426 390 44209 V339 T R S Q T T T V N N L K A G K
Sea Urchin Strong. purpuratus XP_786775 442 49109 S391 Q G N D S S S S T L L T P S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.9 85 81.7 N.A. 77.7 78.7 N.A. N.A. 42 43.7 47.9 N.A. N.A. 26.2 30.8 22.9
Protein Similarity: 100 85.9 85.2 83.4 N.A. 80 80.8 N.A. N.A. 55 55.6 62.8 N.A. N.A. 44.9 47.2 39
P-Site Identity: 100 6.6 6.6 6.6 N.A. 6.6 6.6 N.A. N.A. 13.3 13.3 20 N.A. N.A. 20 6.6 20
P-Site Similarity: 100 26.6 20 20 N.A. 20 20 N.A. N.A. 33.3 20 33.3 N.A. N.A. 33.3 26.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 17 42 9 50 17 0 0 0 0 0 9 17 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 42 9 0 0 0 0 0 % F
% Gly: 0 17 0 0 0 0 0 9 0 0 9 0 42 17 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % I
% Lys: 0 0 0 0 9 0 0 42 9 0 0 9 0 0 17 % K
% Leu: 34 9 0 0 0 0 0 0 0 9 17 9 0 25 9 % L
% Met: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 9 9 0 0 9 0 0 % N
% Pro: 9 42 9 17 9 0 34 0 0 42 17 9 17 25 25 % P
% Gln: 9 0 0 9 0 0 0 9 0 9 0 0 0 9 0 % Q
% Arg: 0 9 0 0 0 0 9 0 0 9 0 9 0 0 0 % R
% Ser: 17 9 17 9 59 42 34 17 9 9 50 59 17 9 0 % S
% Thr: 17 0 50 17 9 9 9 0 17 0 0 9 0 0 0 % T
% Val: 0 0 0 0 0 0 0 17 9 0 0 0 9 0 34 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _