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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSAD All Species: 37.27
Human Site: S420 Identified Species: 68.33
UniProt: Q9Y600 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y600 NP_057073.4 493 55023 S420 C F W F V P P S L R G K Q E S
Chimpanzee Pan troglodytes Q5IS68 594 66879 S521 C F W Y I P Q S L R G V P D S
Rhesus Macaque Macaca mulatta XP_001102580 493 54924 S420 C F W F V P P S L R G K Q D S
Dog Lupus familis XP_849310 495 55396 S422 C F W F V P P S L R G R Q K C
Cat Felis silvestris
Mouse Mus musculus Q9DBE0 493 55126 S420 C F W F V P P S L R G K K E S
Rat Rattus norvegicus Q64611 493 55230 S420 C F W F V P P S L R G K K E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508467 621 70605 S548 C F W Y I P P S L R N M E E G
Chicken Gallus gallus XP_418596 610 68572 S537 C F W Y I P P S L R G M E D N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007349 482 54874 S409 C F W F I P P S L K G K E N S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20228 510 57801 R437 S F W Y V P K R L R G V P H D
Honey Bee Apis mellifera XP_395238 548 62629 P475 V C F W Y V P P S K R Q L Q N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780979 579 65066 S503 C F W F I P A S L R D E E R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M0G4 545 60786 A451 K H F E D Y V A Q D P S F E V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.2 98.3 90 N.A. 89.6 89.6 N.A. 49.9 44.5 N.A. 63.4 N.A. 46.4 48.9 N.A. 45.2
Protein Similarity: 100 61.7 98.9 94.9 N.A. 95.3 95.9 N.A. 65 61.1 N.A. 80.9 N.A. 66.6 65.6 N.A. 62.5
P-Site Identity: 100 60 93.3 80 N.A. 93.3 93.3 N.A. 60 60 N.A. 73.3 N.A. 46.6 6.6 N.A. 53.3
P-Site Similarity: 100 80 100 93.3 N.A. 100 100 N.A. 80 93.3 N.A. 93.3 N.A. 53.3 46.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 23.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % A
% Cys: 77 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 8 0 0 0 0 8 8 0 0 24 8 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 8 31 39 0 % E
% Phe: 0 85 16 54 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 70 0 0 0 8 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 39 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 8 0 0 16 0 39 16 8 0 % K
% Leu: 0 0 0 0 0 0 0 0 85 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 16 % N
% Pro: 0 0 0 0 0 85 70 8 0 0 8 0 16 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 8 0 0 8 24 8 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 77 8 8 0 8 0 % R
% Ser: 8 0 0 0 0 0 0 77 8 0 0 8 0 0 47 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % T
% Val: 8 0 0 0 47 8 8 0 0 0 0 16 0 0 8 % V
% Trp: 0 0 85 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 31 8 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _