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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCN10A
All Species:
17.27
Human Site:
T1181
Identified Species:
42.22
UniProt:
Q9Y5Y9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5Y9
NP_006505.2
1956
220626
T1181
Y
Y
L
D
Q
K
P
T
V
K
A
L
L
E
Y
Chimpanzee
Pan troglodytes
XP_516372
1956
220469
T1181
Y
Y
L
D
Q
K
P
T
V
K
A
L
L
E
Y
Rhesus Macaque
Macaca mulatta
XP_001100281
1957
223189
T1189
I
Y
I
E
Q
R
K
T
I
K
T
M
L
E
Y
Dog
Lupus familis
XP_858252
1960
223552
T1189
I
Y
I
E
Q
R
K
T
I
K
T
M
L
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q6QIY3
1958
220533
R1182
N
Y
L
E
E
K
P
R
V
K
S
V
L
E
Y
Rat
Rattus norvegicus
Q62968
1956
219714
R1182
N
Y
L
E
E
K
P
R
V
K
S
V
L
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232818
2040
231951
N1259
I
Y
L
E
D
R
K
N
I
K
T
M
L
E
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q20JQ7
1784
201644
T1071
G
A
I
K
S
L
R
T
L
R
A
L
R
P
L
Tiger Blowfish
Takifugu rubipres
Q2XVR7
1892
213080
T1099
I
Y
I
E
R
R
R
T
V
K
I
V
L
E
F
Fruit Fly
Dros. melanogaster
P35500
2131
239344
I1330
V
H
L
P
Q
R
P
I
L
Q
D
I
L
Y
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
57.5
57.5
N.A.
82.2
83
N.A.
N.A.
62.5
N.A.
54
54.1
43.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
72.9
72.5
N.A.
89.2
89.8
N.A.
N.A.
75.1
N.A.
68.7
69.1
58.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
46.6
46.6
N.A.
60
60
N.A.
N.A.
40
N.A.
20
40
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
80
N.A.
86.6
86.6
N.A.
N.A.
66.6
N.A.
40
80
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
30
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
10
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
60
20
0
0
0
0
0
0
0
0
80
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
40
0
40
0
0
0
0
10
30
0
10
10
0
0
0
% I
% Lys:
0
0
0
10
0
40
30
0
0
80
0
0
0
0
0
% K
% Leu:
0
0
60
0
0
10
0
0
20
0
0
30
90
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
30
0
0
0
% M
% Asn:
20
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
50
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
50
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
50
20
20
0
10
0
0
10
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
0
0
20
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
60
0
0
30
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
50
0
0
30
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
80
0
0
0
0
0
0
0
0
0
0
0
10
80
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _