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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GMPPB
All Species:
57.88
Human Site:
Y208
Identified Species:
79.58
UniProt:
Q9Y5P6
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5P6
NP_037466.2
360
39834
Y208
M
A
K
E
G
Q
L
Y
A
M
E
L
Q
G
F
Chimpanzee
Pan troglodytes
XP_001165804
387
42605
Y208
M
A
K
E
G
Q
L
Y
A
M
E
L
Q
G
F
Rhesus Macaque
Macaca mulatta
XP_001106890
360
39913
Y208
M
A
K
E
G
Q
L
Y
A
M
E
L
Q
G
F
Dog
Lupus familis
XP_850642
876
95988
Y208
M
A
K
E
G
Q
L
Y
A
M
E
L
Q
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTZ7
360
39898
Y208
M
A
K
E
G
Q
L
Y
A
M
E
L
Q
G
F
Rat
Rattus norvegicus
Q5XIC1
420
46173
Y237
L
A
G
Q
G
Q
I
Y
V
H
L
T
D
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414268
439
48772
Y287
M
A
Q
D
G
Q
L
Y
A
M
E
L
Q
G
F
Frog
Xenopus laevis
Q68EY9
360
40133
Y208
M
A
Q
E
G
Q
L
Y
A
M
E
L
Q
G
F
Zebra Danio
Brachydanio rerio
Q6DBU5
360
40125
Y208
M
A
E
E
G
Q
L
Y
A
M
E
L
Q
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JZB4
369
40430
Y217
M
T
Q
Q
Q
E
L
Y
A
M
D
L
T
G
F
Honey Bee
Apis mellifera
XP_392845
359
39840
Y207
M
A
R
D
G
E
L
Y
A
M
E
L
T
G
F
Nematode Worm
Caenorhab. elegans
A3QMC8
365
40081
Y207
M
A
F
S
G
N
L
Y
A
F
V
L
P
G
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002316262
361
39591
Y209
I
A
A
E
D
K
L
Y
A
M
V
L
P
G
F
Maize
Zea mays
NP_001142302
361
39566
Y209
I
A
A
D
Q
Q
L
Y
A
M
V
L
P
G
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181507
361
39559
Y209
I
A
A
A
Q
G
L
Y
A
M
V
L
P
G
F
Baker's Yeast
Sacchar. cerevisiae
P41940
361
39547
Y209
L
V
E
E
K
Q
L
Y
S
F
D
L
E
G
F
Red Bread Mold
Neurospora crassa
Q7RVR8
364
40035
H209
M
V
R
D
G
Q
L
H
S
F
D
L
E
G
F
Conservation
Percent
Protein Identity:
100
92.7
99.1
39.8
N.A.
98
33.8
N.A.
N.A.
61.5
82.2
81.1
N.A.
68.5
66.3
63
N.A.
Protein Similarity:
100
93
99.4
40.7
N.A.
99.1
48.5
N.A.
N.A.
71.5
92.2
93.3
N.A.
84.2
83.6
76.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
33.3
N.A.
N.A.
86.6
93.3
93.3
N.A.
53.3
73.3
60
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
53.3
N.A.
N.A.
100
100
100
N.A.
80
93.3
60
N.A.
Percent
Protein Identity:
61.2
61.7
N.A.
61.7
57.8
59.6
Protein Similarity:
79.5
79.5
N.A.
79.5
77
79.1
P-Site Identity:
60
60
N.A.
53.3
46.6
46.6
P-Site Similarity:
73.3
73.3
N.A.
60
80
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
83
18
6
0
0
0
0
83
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
6
0
0
0
0
0
18
0
6
0
0
% D
% Glu:
0
0
12
53
0
12
0
0
0
0
53
0
12
0
0
% E
% Phe:
0
0
6
0
0
0
0
0
0
18
0
0
0
0
95
% F
% Gly:
0
0
6
0
71
6
0
0
0
0
0
0
0
100
0
% G
% His:
0
0
0
0
0
0
0
6
0
6
0
0
0
0
0
% H
% Ile:
18
0
0
0
0
0
6
0
0
0
0
0
0
0
6
% I
% Lys:
0
0
30
0
6
6
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
0
0
0
95
0
0
0
6
95
0
0
0
% L
% Met:
71
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% P
% Gln:
0
0
18
12
18
71
0
0
0
0
0
0
48
0
0
% Q
% Arg:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
6
0
0
0
0
12
0
0
0
0
0
0
% S
% Thr:
0
6
0
0
0
0
0
0
0
0
0
6
12
0
0
% T
% Val:
0
12
0
0
0
0
0
0
6
0
24
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
95
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _