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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD2AP
All Species:
18.79
Human Site:
T490
Identified Species:
41.33
UniProt:
Q9Y5K6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5K6
NP_036252.1
639
71451
T490
S
E
N
L
L
H
L
T
A
N
R
P
K
M
P
Chimpanzee
Pan troglodytes
XP_527616
639
71373
T490
S
E
N
L
L
H
L
T
A
N
R
P
K
M
P
Rhesus Macaque
Macaca mulatta
XP_001103871
639
71306
T490
S
E
N
L
L
H
L
T
A
N
R
P
K
M
P
Dog
Lupus familis
XP_532162
656
73578
T507
S
E
N
L
L
H
L
T
A
N
R
P
K
M
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLQ0
637
70413
T490
S
E
N
L
L
H
L
T
A
N
R
P
K
M
P
Rat
Rattus norvegicus
Q925Q9
709
78067
E558
F
D
S
P
S
P
E
E
D
K
E
E
H
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514038
690
76640
E541
F
D
S
P
S
P
E
E
E
R
E
E
H
I
S
Chicken
Gallus gallus
Q5ZLR6
764
85889
R583
P
W
S
L
S
C
L
R
P
A
P
P
L
R
P
Frog
Xenopus laevis
NP_001086432
731
81149
K492
V
E
P
H
S
K
T
K
T
D
L
E
Q
I
L
Zebra Danio
Brachydanio rerio
NP_001008583
657
72788
P504
S
S
E
K
L
S
H
P
T
A
Q
R
P
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786341
875
93543
T519
P
N
R
R
P
P
S
T
F
G
M
P
P
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.2
89
N.A.
86.5
35.9
N.A.
35.6
20.4
50.2
49.1
N.A.
N.A.
N.A.
N.A.
26.6
Protein Similarity:
100
99.6
97.9
92.8
N.A.
90.4
54.5
N.A.
53.4
36.1
66.6
67.4
N.A.
N.A.
N.A.
N.A.
41.1
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
26.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
20
33.3
26.6
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
46
19
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
0
0
0
0
10
10
0
0
0
0
0
% D
% Glu:
0
55
10
0
0
0
19
19
10
0
19
28
0
0
0
% E
% Phe:
19
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
10
0
46
10
0
0
0
0
0
19
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% I
% Lys:
0
0
0
10
0
10
0
10
0
10
0
0
46
10
0
% K
% Leu:
0
0
0
55
55
0
55
0
0
0
10
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
46
10
% M
% Asn:
0
10
46
0
0
0
0
0
0
46
0
0
0
0
0
% N
% Pro:
19
0
10
19
10
28
0
10
10
0
10
64
19
10
55
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
0
0
10
10
0
0
0
10
0
10
46
10
0
10
0
% R
% Ser:
55
10
28
0
37
10
10
0
0
0
0
0
0
0
19
% S
% Thr:
0
0
0
0
0
0
10
55
19
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _