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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD2AP
All Species:
11.21
Human Site:
T465
Identified Species:
24.67
UniProt:
Q9Y5K6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5K6
NP_036252.1
639
71451
T465
S
V
D
F
D
S
L
T
V
R
T
S
K
E
T
Chimpanzee
Pan troglodytes
XP_527616
639
71373
T465
S
V
D
F
D
S
L
T
V
R
T
S
K
E
T
Rhesus Macaque
Macaca mulatta
XP_001103871
639
71306
I465
S
V
D
L
D
S
L
I
V
R
T
S
K
E
T
Dog
Lupus familis
XP_532162
656
73578
T482
S
V
D
L
D
S
F
T
V
R
S
S
K
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLQ0
637
70413
V465
S
V
D
L
D
A
F
V
A
R
N
S
K
E
T
Rat
Rattus norvegicus
Q925Q9
709
78067
R533
S
R
P
K
A
T
G
R
R
P
P
S
Q
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514038
690
76640
R516
T
R
P
K
A
T
G
R
R
P
P
S
Q
S
L
Chicken
Gallus gallus
Q5ZLR6
764
85889
F558
S
W
S
A
H
S
T
F
G
S
T
G
Q
I
R
Frog
Xenopus laevis
NP_001086432
731
81149
H467
K
S
T
E
A
E
L
H
N
K
A
K
T
D
L
Zebra Danio
Brachydanio rerio
NP_001008583
657
72788
G479
P
K
T
V
V
D
I
G
E
K
S
T
E
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786341
875
93543
T494
E
S
T
F
D
N
I
T
I
N
T
E
K
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.2
89
N.A.
86.5
35.9
N.A.
35.6
20.4
50.2
49.1
N.A.
N.A.
N.A.
N.A.
26.6
Protein Similarity:
100
99.6
97.9
92.8
N.A.
90.4
54.5
N.A.
53.4
36.1
66.6
67.4
N.A.
N.A.
N.A.
N.A.
41.1
P-Site Identity:
100
100
86.6
80
N.A.
60
13.3
N.A.
6.6
20
6.6
0
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
86.6
86.6
N.A.
66.6
26.6
N.A.
26.6
26.6
20
33.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
28
10
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
46
0
55
10
0
0
0
0
0
0
0
10
0
% D
% Glu:
10
0
0
10
0
10
0
0
10
0
0
10
10
46
0
% E
% Phe:
0
0
0
28
0
0
19
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
19
10
10
0
0
10
0
0
0
% G
% His:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
19
10
10
0
0
0
0
10
0
% I
% Lys:
10
10
0
19
0
0
0
0
0
19
0
10
55
0
0
% K
% Leu:
0
0
0
28
0
0
37
0
0
0
0
0
0
10
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
10
10
0
0
0
0
% N
% Pro:
10
0
19
0
0
0
0
0
0
19
19
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% Q
% Arg:
0
19
0
0
0
0
0
19
19
46
0
0
0
0
10
% R
% Ser:
64
19
10
0
0
46
0
0
0
10
19
64
0
19
0
% S
% Thr:
10
0
28
0
0
19
10
37
0
0
46
10
10
10
55
% T
% Val:
0
46
0
10
10
0
0
10
37
0
0
0
0
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _