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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD2AP
All Species:
17.58
Human Site:
T229
Identified Species:
38.67
UniProt:
Q9Y5K6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5K6
NP_036252.1
639
71451
T229
E
G
S
V
K
L
R
T
R
T
S
S
S
E
T
Chimpanzee
Pan troglodytes
XP_527616
639
71373
T229
E
G
S
V
K
L
R
T
R
T
S
S
S
E
T
Rhesus Macaque
Macaca mulatta
XP_001103871
639
71306
T229
E
G
S
V
K
L
R
T
R
T
S
S
S
E
T
Dog
Lupus familis
XP_532162
656
73578
T246
E
G
S
V
K
L
R
T
R
T
S
G
S
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLQ0
637
70413
T229
E
G
S
V
K
L
R
T
R
T
S
S
S
E
T
Rat
Rattus norvegicus
Q925Q9
709
78067
R271
K
D
K
P
I
K
L
R
P
R
S
I
E
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514038
690
76640
R254
K
D
K
P
I
K
L
R
P
R
S
I
E
V
E
Chicken
Gallus gallus
Q5ZLR6
764
85889
I274
D
K
L
S
A
V
D
I
A
S
L
L
G
N
V
Frog
Xenopus laevis
NP_001086432
731
81149
A235
K
L
K
T
R
M
P
A
P
E
P
E
V
K
K
Zebra Danio
Brachydanio rerio
NP_001008583
657
72788
P243
L
R
T
S
L
K
G
P
S
E
N
M
E
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786341
875
93543
P273
A
K
A
A
E
S
H
P
F
A
L
K
R
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.2
89
N.A.
86.5
35.9
N.A.
35.6
20.4
50.2
49.1
N.A.
N.A.
N.A.
N.A.
26.6
Protein Similarity:
100
99.6
97.9
92.8
N.A.
90.4
54.5
N.A.
53.4
36.1
66.6
67.4
N.A.
N.A.
N.A.
N.A.
41.1
P-Site Identity:
100
100
100
86.6
N.A.
100
6.6
N.A.
6.6
0
0
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
100
13.3
N.A.
13.3
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
10
0
0
10
10
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
46
0
0
0
10
0
0
0
0
19
0
10
28
46
19
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
46
0
0
0
0
10
0
0
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
19
0
0
10
0
0
0
19
0
0
10
% I
% Lys:
28
19
28
0
46
28
0
0
0
0
0
10
0
19
10
% K
% Leu:
10
10
10
0
10
46
19
0
0
0
19
10
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% N
% Pro:
0
0
0
19
0
0
10
19
28
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
10
0
46
19
46
19
0
0
10
0
0
% R
% Ser:
0
0
46
19
0
10
0
0
10
10
64
37
46
0
10
% S
% Thr:
0
0
10
10
0
0
0
46
0
46
0
0
0
0
46
% T
% Val:
0
0
0
46
0
10
0
0
0
0
0
0
10
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _