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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD2AP
All Species:
14.24
Human Site:
S432
Identified Species:
31.33
UniProt:
Q9Y5K6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5K6
NP_036252.1
639
71451
S432
K
I
N
G
E
V
S
S
I
S
S
K
F
E
T
Chimpanzee
Pan troglodytes
XP_527616
639
71373
S432
K
I
N
G
E
V
S
S
I
S
S
K
F
E
T
Rhesus Macaque
Macaca mulatta
XP_001103871
639
71306
T432
K
I
N
G
E
V
S
T
I
A
S
K
F
E
T
Dog
Lupus familis
XP_532162
656
73578
T449
K
I
N
G
E
V
S
T
I
S
S
K
F
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLQ0
637
70413
I432
K
I
N
G
E
V
S
I
I
S
S
K
I
D
T
Rat
Rattus norvegicus
Q925Q9
709
78067
D500
I
L
D
K
D
L
S
D
R
S
N
D
I
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514038
690
76640
E483
P
P
D
K
D
L
P
E
R
S
N
D
I
D
L
Chicken
Gallus gallus
Q5ZLR6
764
85889
S525
I
T
V
S
C
S
T
S
Q
D
L
H
E
W
L
Frog
Xenopus laevis
NP_001086432
731
81149
L434
K
P
N
G
D
L
L
L
I
R
P
K
P
E
S
Zebra Danio
Brachydanio rerio
NP_001008583
657
72788
P446
D
L
P
L
T
P
S
P
A
A
K
Q
V
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786341
875
93543
Q461
P
T
A
L
T
K
P
Q
V
P
A
S
R
P
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.2
89
N.A.
86.5
35.9
N.A.
35.6
20.4
50.2
49.1
N.A.
N.A.
N.A.
N.A.
26.6
Protein Similarity:
100
99.6
97.9
92.8
N.A.
90.4
54.5
N.A.
53.4
36.1
66.6
67.4
N.A.
N.A.
N.A.
N.A.
41.1
P-Site Identity:
100
100
86.6
93.3
N.A.
80
13.3
N.A.
6.6
6.6
40
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
53.3
N.A.
40
13.3
60
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
10
19
10
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
19
0
28
0
0
10
0
10
0
19
0
28
0
% D
% Glu:
0
0
0
0
46
0
0
10
0
0
0
0
10
46
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
37
0
0
% F
% Gly:
0
0
0
55
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
19
46
0
0
0
0
0
10
55
0
0
0
28
0
0
% I
% Lys:
55
0
0
19
0
10
0
0
0
0
10
55
0
0
0
% K
% Leu:
0
19
0
19
0
28
10
10
0
0
10
0
0
0
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
55
0
0
0
0
0
0
0
19
0
0
0
10
% N
% Pro:
19
19
10
0
0
10
19
10
0
10
10
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
10
0
0
10
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
19
10
0
0
10
0
0
% R
% Ser:
0
0
0
10
0
10
64
28
0
55
46
10
0
0
10
% S
% Thr:
0
19
0
0
19
0
10
19
0
0
0
0
0
0
46
% T
% Val:
0
0
10
0
0
46
0
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _