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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD2AP
All Species:
12.73
Human Site:
S249
Identified Species:
28
UniProt:
Q9Y5K6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5K6
NP_036252.1
639
71451
S249
E
K
P
L
I
L
Q
S
L
G
P
K
T
Q
S
Chimpanzee
Pan troglodytes
XP_527616
639
71373
S249
E
K
P
L
I
L
Q
S
L
G
P
K
T
Q
S
Rhesus Macaque
Macaca mulatta
XP_001103871
639
71306
S249
E
K
P
L
I
L
P
S
L
G
S
K
T
Q
S
Dog
Lupus familis
XP_532162
656
73578
S266
E
K
P
L
I
I
Q
S
V
G
S
K
T
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLQ0
637
70413
P249
E
K
P
L
I
L
Q
P
L
G
S
R
T
Q
N
Rat
Rattus norvegicus
Q925Q9
709
78067
K291
V
E
K
T
I
G
K
K
L
P
P
A
T
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514038
690
76640
K274
V
E
K
T
V
G
K
K
L
P
P
A
T
A
T
Chicken
Gallus gallus
Q5ZLR6
764
85889
A294
F
Q
Q
T
L
N
Q
A
L
E
D
V
A
K
L
Frog
Xenopus laevis
NP_001086432
731
81149
I255
P
V
Q
P
S
G
S
I
K
V
L
R
S
A
S
Zebra Danio
Brachydanio rerio
NP_001008583
657
72788
P263
P
L
P
S
A
T
K
P
T
P
L
S
T
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786341
875
93543
E293
H
E
E
K
K
D
E
E
K
K
E
D
K
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.2
89
N.A.
86.5
35.9
N.A.
35.6
20.4
50.2
49.1
N.A.
N.A.
N.A.
N.A.
26.6
Protein Similarity:
100
99.6
97.9
92.8
N.A.
90.4
54.5
N.A.
53.4
36.1
66.6
67.4
N.A.
N.A.
N.A.
N.A.
41.1
P-Site Identity:
100
100
86.6
80
N.A.
73.3
26.6
N.A.
20
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
93.3
N.A.
86.6
46.6
N.A.
46.6
40
20
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
0
0
0
19
10
19
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
10
10
0
0
0
% D
% Glu:
46
28
10
0
0
0
10
10
0
10
10
0
0
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
28
0
0
0
46
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
55
10
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
46
19
10
10
0
28
19
19
10
0
37
10
10
0
% K
% Leu:
0
10
0
46
10
37
0
0
64
0
19
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
10
% N
% Pro:
19
0
55
10
0
0
10
19
0
28
37
0
0
10
0
% P
% Gln:
0
10
19
0
0
0
46
0
0
0
0
0
0
46
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% R
% Ser:
0
0
0
10
10
0
10
37
0
0
28
10
10
10
46
% S
% Thr:
0
0
0
28
0
10
0
0
10
0
0
0
73
0
19
% T
% Val:
19
10
0
0
10
0
0
0
10
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _