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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD2AP
All Species:
18.79
Human Site:
S180
Identified Species:
41.33
UniProt:
Q9Y5K6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5K6
NP_036252.1
639
71451
S180
T
H
E
A
Q
D
D
S
E
T
V
L
A
G
P
Chimpanzee
Pan troglodytes
XP_527616
639
71373
S180
T
H
E
A
Q
D
D
S
E
T
V
L
A
G
P
Rhesus Macaque
Macaca mulatta
XP_001103871
639
71306
S180
T
R
E
A
Q
D
D
S
E
T
V
L
G
G
P
Dog
Lupus familis
XP_532162
656
73578
S197
T
H
E
A
Q
E
D
S
E
T
V
F
T
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLQ0
637
70413
S180
T
H
N
A
Q
E
E
S
E
V
P
L
T
G
P
Rat
Rattus norvegicus
Q925Q9
709
78067
L170
G
I
S
Q
D
E
Q
L
S
K
S
R
P
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514038
690
76640
L198
G
I
T
Q
E
E
Q
L
I
K
P
S
L
R
E
Chicken
Gallus gallus
Q5ZLR6
764
85889
L224
S
P
K
A
L
K
G
L
E
S
T
Q
L
T
K
Frog
Xenopus laevis
NP_001086432
731
81149
S178
S
Q
E
S
T
E
D
S
E
Q
S
V
T
T
P
Zebra Danio
Brachydanio rerio
NP_001008583
657
72788
Q195
N
S
D
V
T
E
E
Q
D
T
R
D
G
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786341
875
93543
S217
A
K
S
E
A
V
S
S
S
G
G
T
T
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.2
89
N.A.
86.5
35.9
N.A.
35.6
20.4
50.2
49.1
N.A.
N.A.
N.A.
N.A.
26.6
Protein Similarity:
100
99.6
97.9
92.8
N.A.
90.4
54.5
N.A.
53.4
36.1
66.6
67.4
N.A.
N.A.
N.A.
N.A.
41.1
P-Site Identity:
100
100
86.6
80
N.A.
60
0
N.A.
0
13.3
33.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
86.6
86.6
N.A.
73.3
6.6
N.A.
13.3
33.3
60
33.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
55
10
0
0
0
0
0
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
28
46
0
10
0
0
10
0
0
0
% D
% Glu:
0
0
46
10
10
55
19
0
64
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
19
0
0
0
0
0
10
0
0
10
10
0
19
46
10
% G
% His:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
10
10
0
0
10
0
0
0
19
0
0
0
0
10
% K
% Leu:
0
0
0
0
10
0
0
28
0
0
0
37
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
19
0
10
10
55
% P
% Gln:
0
10
0
19
46
0
19
10
0
10
0
10
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
10
10
0
10
0
% R
% Ser:
19
10
19
10
0
0
10
64
19
10
19
10
0
0
10
% S
% Thr:
46
0
10
0
19
0
0
0
0
46
10
10
37
28
0
% T
% Val:
0
0
0
10
0
10
0
0
0
10
37
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _