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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UTP18 All Species: 41.82
Human Site: T250 Identified Species: 57.5
UniProt: Q9Y5J1 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5J1 NP_057085.2 556 62004 T250 H A N A E R P T V A R I S S V
Chimpanzee Pan troglodytes XP_001159780 541 60423 T238 E D D L L Q R T G N F I S T S
Rhesus Macaque Macaca mulatta XP_001096494 575 64303 T267 P A N A E R P T V A R I S S V
Dog Lupus familis XP_548208 555 61848 T249 H A N A E R P T T A R I S S V
Cat Felis silvestris
Mouse Mus musculus Q5SSI6 552 61200 T246 P A N A E R P T T A R I S S V
Rat Rattus norvegicus NP_001128511 546 60552 T240 P A N A E R P T T A R I S S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519850 695 76613 S305 D A N C Q L P S S G P L S S V
Chicken Gallus gallus
Frog Xenopus laevis NP_001090056 521 58783 S215 N A N N E R M S P V P L T T V
Zebra Danio Brachydanio rerio NP_001070232 509 57076 S203 N A N S E C V S E A Q L T S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7P1 506 56928 A204 D L N R A T Y A E G N A T S I
Honey Bee Apis mellifera XP_001123029 455 51426 V152 S N K Y K L L V G P I V S S V
Nematode Worm Caenorhab. elegans P42000 429 47754 L134 F H K T R P V L I V A D Q G G
Sea Urchin Strong. purpuratus XP_784892 453 50681 T150 N L N K E Q P T E G M V T A L
Poplar Tree Populus trichocarpa XP_002306819 491 54950 S188 D A N A E D P S N G P I N S V
Maize Zea mays NP_001132144 556 61790 S253 D A N I Q D P S S G P I N S V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FMU5 546 60970 S243 D A N A A D P S N G P I N S V
Baker's Yeast Sacchar. cerevisiae P40362 594 66405 S247 D A N A S H P S H S A I Q S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.3 89.5 89.2 N.A. 79.5 81.8 N.A. 45.3 N.A. 52.1 46.9 N.A. 29.8 32 21.3 36.1
Protein Similarity: 100 92.9 91.4 93.3 N.A. 87.2 88.6 N.A. 58.2 N.A. 69.7 66.3 N.A. 48.3 51.4 39.9 55
P-Site Identity: 100 20 93.3 93.3 N.A. 86.6 86.6 N.A. 40 N.A. 33.3 40 N.A. 13.3 20 0 26.6
P-Site Similarity: 100 40 93.3 93.3 N.A. 86.6 86.6 N.A. 60 N.A. 66.6 80 N.A. 26.6 33.3 6.6 66.6
Percent
Protein Identity: 32.7 32.1 N.A. 34.3 24 N.A.
Protein Similarity: 51.8 52.3 N.A. 52.7 47.3 N.A.
P-Site Identity: 53.3 40 N.A. 46.6 40 N.A.
P-Site Similarity: 66.6 60 N.A. 60 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 71 0 48 12 0 0 6 0 36 12 6 0 6 0 % A
% Cys: 0 0 0 6 0 6 0 0 0 0 0 0 0 0 0 % C
% Asp: 36 6 6 0 0 18 0 0 0 0 0 6 0 0 0 % D
% Glu: 6 0 0 0 53 0 0 0 18 0 0 0 0 0 0 % E
% Phe: 6 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 12 36 0 0 0 6 6 % G
% His: 12 6 0 0 0 6 0 0 6 0 0 0 0 0 0 % H
% Ile: 0 0 0 6 0 0 0 0 6 0 6 59 0 0 6 % I
% Lys: 0 0 12 6 6 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 12 0 6 6 12 6 6 0 0 0 18 0 0 12 % L
% Met: 0 0 0 0 0 0 6 0 0 0 6 0 0 0 0 % M
% Asn: 18 6 83 6 0 0 0 0 12 6 6 0 18 0 0 % N
% Pro: 18 0 0 0 0 6 65 0 6 6 30 0 0 0 0 % P
% Gln: 0 0 0 0 12 12 0 0 0 0 6 0 12 0 0 % Q
% Arg: 0 0 0 6 6 36 6 0 0 0 30 0 0 0 0 % R
% Ser: 6 0 0 6 6 0 0 42 12 6 0 0 48 77 6 % S
% Thr: 0 0 0 6 0 6 0 42 18 0 0 0 24 12 0 % T
% Val: 0 0 0 0 0 0 12 6 12 12 0 12 0 0 71 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 6 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _