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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT16H All Species: 31.82
Human Site: Y530 Identified Species: 43.75
UniProt: Q9Y5B9 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5B9 NP_009123.1 1047 119914 Y530 H I R E M K I Y I D K K Y E T
Chimpanzee Pan troglodytes XP_001152860 569 64563 N96 A N T K G N E N A N G A P A I
Rhesus Macaque Macaca mulatta XP_001096507 887 101637 T416 V D E D G P A T V L T S V K K
Dog Lupus familis XP_851566 1047 119940 Y530 H I R E M K I Y I D K K Y E T
Cat Felis silvestris
Mouse Mus musculus Q920B9 1047 119806 Y530 H I R E M K I Y I D K K Y E T
Rat Rattus norvegicus NP_001100731 1047 119847 Y530 H I R E M K I Y I D K K Y E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506385 1063 120394 Y508 H I R E M K I Y I D K K Y E T
Chicken Gallus gallus
Frog Xenopus laevis Q9W603 1035 118422 Y532 E L R E M K L Y I D K K Y E T
Zebra Danio Brachydanio rerio NP_001091053 1033 118165 F531 D I R D M K I F I D K K H E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRG6 1083 123565 Y536 E V K E L K L Y V D K K Y E T
Honey Bee Apis mellifera XP_624006 1112 126368 Y536 E V K E L K L Y V D K K Y E T
Nematode Worm Caenorhab. elegans Q9N5R9 1030 116847 F530 D V Q K M L I F V D R K Y D S
Sea Urchin Strong. purpuratus XP_788298 627 71966 P156 L R I N F H H P G S T M G K T
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6B1 1055 118486 Q544 F V R D L V I Q V D Q K N E A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82491 1074 120567 Q556 P H K E L M I Q V D T R N E A
Baker's Yeast Sacchar. cerevisiae P32558 1035 118612 H554 N I R D L R I H V D W K S Q T
Red Bread Mold Neurospora crassa Q8X0X6 1032 118039 V548 K V K D M G I V I D Q K N A T
Conservation
Percent
Protein Identity: 100 54.2 84.7 99.8 N.A. 98.6 99 N.A. 91.1 N.A. 86.8 83.7 N.A. 58.9 58.5 47 41.1
Protein Similarity: 100 54.3 84.7 100 N.A. 100 100 N.A. 93.7 N.A. 93.5 92.1 N.A. 76.4 75.9 66.5 49.7
P-Site Identity: 100 0 0 100 N.A. 100 100 N.A. 100 N.A. 80 73.3 N.A. 60 60 33.3 6.6
P-Site Similarity: 100 13.3 20 100 N.A. 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 93.3 93.3 86.6 13.3
Percent
Protein Identity: N.A. 36.7 N.A. 34.9 35.4 38.3
Protein Similarity: N.A. 58.9 N.A. 56.5 55.9 59.6
P-Site Identity: N.A. 33.3 N.A. 26.6 40 40
P-Site Similarity: N.A. 66.6 N.A. 53.3 86.6 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 0 0 6 0 6 0 0 6 0 12 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 6 0 30 0 0 0 0 0 83 0 0 0 6 0 % D
% Glu: 18 0 6 53 0 0 6 0 0 0 0 0 0 65 0 % E
% Phe: 6 0 0 0 6 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 12 6 0 0 6 0 6 0 6 0 0 % G
% His: 30 6 0 0 0 6 6 6 0 0 0 0 6 0 0 % H
% Ile: 0 42 6 0 0 0 65 0 48 0 0 0 0 0 6 % I
% Lys: 6 0 24 12 0 53 0 0 0 0 53 77 0 12 6 % K
% Leu: 6 6 0 0 30 6 18 0 0 6 0 0 0 0 0 % L
% Met: 0 0 0 0 53 6 0 0 0 0 0 6 0 0 0 % M
% Asn: 6 6 0 6 0 6 0 6 0 6 0 0 18 0 0 % N
% Pro: 6 0 0 0 0 6 0 6 0 0 0 0 6 0 0 % P
% Gln: 0 0 6 0 0 0 0 12 0 0 12 0 0 6 0 % Q
% Arg: 0 6 53 0 0 6 0 0 0 0 6 6 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 6 0 6 6 0 6 % S
% Thr: 0 0 6 0 0 0 0 6 0 0 18 0 0 0 71 % T
% Val: 6 30 0 0 0 6 0 6 42 0 0 0 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 48 0 0 0 0 53 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _