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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT16H All Species: 25.15
Human Site: Y369 Identified Species: 34.58
UniProt: Q9Y5B9 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5B9 NP_009123.1 1047 119914 Y369 V I N S K N Q Y K L K K G M V
Chimpanzee Pan troglodytes XP_001152860 569 64563
Rhesus Macaque Macaca mulatta XP_001096507 887 101637 N285 R F K S Y C S N L V R T L M V
Dog Lupus familis XP_851566 1047 119940 Y369 V I N S K N Q Y K L K K G M V
Cat Felis silvestris
Mouse Mus musculus Q920B9 1047 119806 Y369 V I N S K N Q Y K L K K G M V
Rat Rattus norvegicus NP_001100731 1047 119847 Y369 V I N S K N Q Y K L K K G M V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506385 1063 120394 Y347 V I N S K N Q Y K L K K G M V
Chicken Gallus gallus
Frog Xenopus laevis Q9W603 1035 118422 Y370 V I N N K N Q Y K L K K G M V
Zebra Danio Brachydanio rerio NP_001091053 1033 118165 F369 V I N Q K N Q F K L K R G M V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRG6 1083 123565 A370 V I G P K C Q A L L K K N M V
Honey Bee Apis mellifera XP_624006 1112 126368 A372 L I G P K I H A T L K K G M V
Nematode Worm Caenorhab. elegans Q9N5R9 1030 116847 E369 A I S A K C D E V V K A G M V
Sea Urchin Strong. purpuratus XP_788298 627 71966 K25 E E D K E V Q K K E Q E Q L L
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6B1 1055 118486 R385 N L N A K N D R R I K K G M V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82491 1074 120567 K398 N I N A K N D K V L R P K M A
Baker's Yeast Sacchar. cerevisiae P32558 1035 118612 Y385 I L N V K N D Y R K I Q R G D
Red Bread Mold Neurospora crassa Q8X0X6 1032 118039 R381 I L N N K N T R T L K D G M T
Conservation
Percent
Protein Identity: 100 54.2 84.7 99.8 N.A. 98.6 99 N.A. 91.1 N.A. 86.8 83.7 N.A. 58.9 58.5 47 41.1
Protein Similarity: 100 54.3 84.7 100 N.A. 100 100 N.A. 93.7 N.A. 93.5 92.1 N.A. 76.4 75.9 66.5 49.7
P-Site Identity: 100 0 20 100 N.A. 100 100 N.A. 100 N.A. 93.3 80 N.A. 60 53.3 40 13.3
P-Site Similarity: 100 0 33.3 100 N.A. 100 100 N.A. 100 N.A. 100 93.3 N.A. 60 60 60 53.3
Percent
Protein Identity: N.A. 36.7 N.A. 34.9 35.4 38.3
Protein Similarity: N.A. 58.9 N.A. 56.5 55.9 59.6
P-Site Identity: N.A. 53.3 N.A. 40 26.6 46.6
P-Site Similarity: N.A. 80 N.A. 53.3 53.3 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 18 0 0 0 12 0 0 0 6 0 0 6 % A
% Cys: 0 0 0 0 0 18 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 6 0 0 0 24 0 0 0 0 6 0 0 6 % D
% Glu: 6 6 0 0 6 0 0 6 0 6 0 6 0 0 0 % E
% Phe: 0 6 0 0 0 0 0 6 0 0 0 0 0 0 0 % F
% Gly: 0 0 12 0 0 0 0 0 0 0 0 0 65 6 0 % G
% His: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % H
% Ile: 12 65 0 0 0 6 0 0 0 6 6 0 0 0 0 % I
% Lys: 0 0 6 6 83 0 0 12 48 6 71 53 6 0 0 % K
% Leu: 6 18 0 0 0 0 0 0 12 65 0 0 6 6 6 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 83 0 % M
% Asn: 12 0 65 12 0 65 0 6 0 0 0 0 6 0 0 % N
% Pro: 0 0 0 12 0 0 0 0 0 0 0 6 0 0 0 % P
% Gln: 0 0 0 6 0 0 53 0 0 0 6 6 6 0 0 % Q
% Arg: 6 0 0 0 0 0 0 12 12 0 12 6 6 0 0 % R
% Ser: 0 0 6 36 0 0 6 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 6 0 12 0 0 6 0 0 6 % T
% Val: 48 0 0 6 0 6 0 0 12 12 0 0 0 0 71 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 0 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _