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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUPT16H
All Species:
52.12
Human Site:
S558
Identified Species:
71.67
UniProt:
Q9Y5B9
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y5B9
NP_009123.1
1047
119914
S558
I
A
T
I
K
N
I
S
M
S
V
E
G
D
Y
Chimpanzee
Pan troglodytes
XP_001152860
569
64563
A124
S
F
D
K
M
I
E
A
I
K
E
S
K
N
G
Rhesus Macaque
Macaca mulatta
XP_001096507
887
101637
K444
E
E
E
E
E
E
E
K
D
E
A
E
D
L
L
Dog
Lupus familis
XP_851566
1047
119940
S558
I
A
T
I
K
N
I
S
M
S
V
E
G
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q920B9
1047
119806
S558
I
A
T
I
K
N
I
S
M
S
V
E
G
D
Y
Rat
Rattus norvegicus
NP_001100731
1047
119847
S558
I
A
T
I
K
N
I
S
M
S
V
E
G
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506385
1063
120394
S536
I
A
T
I
K
N
I
S
M
S
V
E
G
D
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9W603
1035
118422
S560
I
A
T
I
K
N
I
S
M
S
V
E
G
D
Y
Zebra Danio
Brachydanio rerio
NP_001091053
1033
118165
S559
I
A
T
I
K
N
I
S
M
S
V
E
G
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRG6
1083
123565
S564
I
S
T
I
K
N
I
S
Q
S
V
E
G
E
Y
Honey Bee
Apis mellifera
XP_624006
1112
126368
S564
I
S
T
I
K
N
I
S
Q
S
V
E
G
D
Y
Nematode Worm
Caenorhab. elegans
Q9N5R9
1030
116847
S558
I
S
M
I
K
N
C
S
Q
S
V
E
G
D
F
Sea Urchin
Strong. purpuratus
XP_788298
627
71966
S184
K
E
L
T
Y
R
S
S
N
T
K
N
P
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q8H6B1
1055
118486
T572
V
S
T
V
K
S
V
T
S
H
Q
D
N
R
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82491
1074
120567
S584
V
A
T
I
R
T
V
S
G
N
Q
D
T
N
R
Baker's Yeast
Sacchar. cerevisiae
P32558
1035
118612
S582
I
N
S
Y
K
N
G
S
K
N
E
E
G
E
Y
Red Bread Mold
Neurospora crassa
Q8X0X6
1032
118039
S576
I
N
T
I
K
N
A
S
K
S
D
E
G
E
W
Conservation
Percent
Protein Identity:
100
54.2
84.7
99.8
N.A.
98.6
99
N.A.
91.1
N.A.
86.8
83.7
N.A.
58.9
58.5
47
41.1
Protein Similarity:
100
54.3
84.7
100
N.A.
100
100
N.A.
93.7
N.A.
93.5
92.1
N.A.
76.4
75.9
66.5
49.7
P-Site Identity:
100
0
6.6
100
N.A.
100
100
N.A.
100
N.A.
100
100
N.A.
80
86.6
66.6
6.6
P-Site Similarity:
100
20
13.3
100
N.A.
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
93.3
80
13.3
Percent
Protein Identity:
N.A.
36.7
N.A.
34.9
35.4
38.3
Protein Similarity:
N.A.
58.9
N.A.
56.5
55.9
59.6
P-Site Identity:
N.A.
13.3
N.A.
26.6
46.6
60
P-Site Similarity:
N.A.
60
N.A.
66.6
66.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
48
0
0
0
0
6
6
0
0
6
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
0
0
0
0
6
0
6
12
6
53
0
% D
% Glu:
6
12
6
6
6
6
12
0
0
6
12
77
0
18
6
% E
% Phe:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
6
% F
% Gly:
0
0
0
0
0
0
6
0
6
0
0
0
71
6
6
% G
% His:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% H
% Ile:
71
0
0
71
0
6
53
0
6
0
0
0
0
0
0
% I
% Lys:
6
0
0
6
77
0
0
6
12
6
6
0
6
0
0
% K
% Leu:
0
0
6
0
0
0
0
0
0
0
0
0
0
6
6
% L
% Met:
0
0
6
0
6
0
0
0
42
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
71
0
0
6
12
0
6
6
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
18
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
6
6
0
0
0
0
0
0
0
6
6
% R
% Ser:
6
24
6
0
0
6
6
83
6
65
0
6
0
0
0
% S
% Thr:
0
0
71
6
0
6
0
6
0
6
0
0
6
0
6
% T
% Val:
12
0
0
6
0
0
12
0
0
0
59
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% W
% Tyr:
0
0
0
6
6
0
0
0
0
0
0
0
0
0
59
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _