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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT16H All Species: 27.88
Human Site: S516 Identified Species: 38.33
UniProt: Q9Y5B9 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5B9 NP_009123.1 1047 119914 S516 N V S Y K N P S L M P K E P H
Chimpanzee Pan troglodytes XP_001152860 569 64563 V82 F M A S K K K V E F L K Q I A
Rhesus Macaque Macaca mulatta XP_001096507 887 101637 F402 E E K T Y A L F I G D T V L V
Dog Lupus familis XP_851566 1047 119940 S516 N V S Y K N P S L M P K E P H
Cat Felis silvestris
Mouse Mus musculus Q920B9 1047 119806 S516 N V S Y K N P S L M P K E P H
Rat Rattus norvegicus NP_001100731 1047 119847 S516 N V S Y K N P S L M P K E P H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506385 1063 120394 A494 N V S Y K N P A L M P K E P H
Chicken Gallus gallus
Frog Xenopus laevis Q9W603 1035 118422 S518 N V S Y K N A S Q V P K E P E
Zebra Danio Brachydanio rerio NP_001091053 1033 118165 S517 N V S Y K N V S Q M P K E K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRG6 1083 123565 S522 T V S Y K S I S Q M P R E P E
Honey Bee Apis mellifera XP_624006 1112 126368 S522 T I S Y K S L S H M P R E P E
Nematode Worm Caenorhab. elegans Q9N5R9 1030 116847 E516 N V S Y K T E E R F P Q D A D
Sea Urchin Strong. purpuratus XP_788298 627 71966 V142 I K N I S Q S V E G N Y T Y L
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6B1 1055 118486 K530 S N E L V A Y K N V N D V P F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82491 1074 120567 Y542 T S A D V V A Y K N V N D M P
Baker's Yeast Sacchar. cerevisiae P32558 1035 118612 R540 K K Y E S Y V R D S Q L P T N
Red Bread Mold Neurospora crassa Q8X0X6 1032 118039 R534 K R F E S Y K R D N Q F P P K
Conservation
Percent
Protein Identity: 100 54.2 84.7 99.8 N.A. 98.6 99 N.A. 91.1 N.A. 86.8 83.7 N.A. 58.9 58.5 47 41.1
Protein Similarity: 100 54.3 84.7 100 N.A. 100 100 N.A. 93.7 N.A. 93.5 92.1 N.A. 76.4 75.9 66.5 49.7
P-Site Identity: 100 13.3 0 100 N.A. 100 100 N.A. 93.3 N.A. 73.3 73.3 N.A. 60 53.3 40 0
P-Site Similarity: 100 33.3 6.6 100 N.A. 100 100 N.A. 100 N.A. 80 73.3 N.A. 73.3 73.3 53.3 6.6
Percent
Protein Identity: N.A. 36.7 N.A. 34.9 35.4 38.3
Protein Similarity: N.A. 58.9 N.A. 56.5 55.9 59.6
P-Site Identity: N.A. 6.6 N.A. 0 0 6.6
P-Site Similarity: N.A. 20 N.A. 13.3 6.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 12 12 6 0 0 0 0 0 6 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 6 0 0 0 0 12 0 6 6 12 0 12 % D
% Glu: 6 6 6 12 0 0 6 6 12 0 0 0 53 0 18 % E
% Phe: 6 0 6 0 0 0 0 6 0 12 0 6 0 0 6 % F
% Gly: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 30 % H
% Ile: 6 6 0 6 0 0 6 0 6 0 0 0 0 6 0 % I
% Lys: 12 12 6 0 65 6 12 6 6 0 0 48 0 6 6 % K
% Leu: 0 0 0 6 0 0 12 0 30 0 6 6 0 6 6 % L
% Met: 0 6 0 0 0 0 0 0 0 48 0 0 0 6 0 % M
% Asn: 48 6 6 0 0 42 0 0 6 12 12 6 0 0 6 % N
% Pro: 0 0 0 0 0 0 30 0 0 0 59 0 12 59 6 % P
% Gln: 0 0 0 0 0 6 0 0 18 0 12 6 6 0 0 % Q
% Arg: 0 6 0 0 0 0 0 12 6 0 0 12 0 0 0 % R
% Ser: 6 6 59 6 18 12 6 48 0 6 0 0 0 0 0 % S
% Thr: 18 0 0 6 0 6 0 0 0 0 0 6 6 6 0 % T
% Val: 0 53 0 0 12 6 12 12 0 12 6 0 12 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 59 6 12 6 6 0 0 0 6 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _