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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT16H All Species: 19.09
Human Site: S113 Identified Species: 26.25
UniProt: Q9Y5B9 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5B9 NP_009123.1 1047 119914 S113 L I R E K N E S N K S S F D K
Chimpanzee Pan troglodytes XP_001152860 569 64563
Rhesus Macaque Macaca mulatta XP_001096507 887 101637 T54 A K S T A L Q T W L F G Y E L
Dog Lupus familis XP_851566 1047 119940 S113 L I R E K N E S N K S S F D K
Cat Felis silvestris
Mouse Mus musculus Q920B9 1047 119806 S113 L V R E K N E S N K S S F D K
Rat Rattus norvegicus NP_001100731 1047 119847 S113 L V R E K N E S N K S S F D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506385 1063 120394 G113 S K N G K K I G V F S K D K F
Chicken Gallus gallus
Frog Xenopus laevis Q9W603 1035 118422 E113 L V R E K Q N E S N K G N F D
Zebra Danio Brachydanio rerio NP_001091053 1033 118165 S113 L V R E K N E S N K V N F D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRG6 1083 123565 K114 L V R D R T D K D Q G N F E K
Honey Bee Apis mellifera XP_624006 1112 126368 E116 L V R D R N D E D K A N F A K
Nematode Worm Caenorhab. elegans Q9N5R9 1030 116847 K113 L L R D K T D K D A G N F E K
Sea Urchin Strong. purpuratus XP_788298 627 71966
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6B1 1055 118486 D126 T K N S D G A D L M D D I V H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82491 1074 120567 G136 P K G D D G T G L M D A I F R
Baker's Yeast Sacchar. cerevisiae P32558 1035 118612 K114 N K E P E L N K K L F D D V I
Red Bread Mold Neurospora crassa Q8X0X6 1032 118039 K119 E N E K L F I K I T D A I K A
Conservation
Percent
Protein Identity: 100 54.2 84.7 99.8 N.A. 98.6 99 N.A. 91.1 N.A. 86.8 83.7 N.A. 58.9 58.5 47 41.1
Protein Similarity: 100 54.3 84.7 100 N.A. 100 100 N.A. 93.7 N.A. 93.5 92.1 N.A. 76.4 75.9 66.5 49.7
P-Site Identity: 100 0 0 100 N.A. 93.3 93.3 N.A. 13.3 N.A. 26.6 80 N.A. 26.6 40 33.3 0
P-Site Similarity: 100 0 26.6 100 N.A. 100 100 N.A. 13.3 N.A. 40 93.3 N.A. 80 86.6 73.3 0
Percent
Protein Identity: N.A. 36.7 N.A. 34.9 35.4 38.3
Protein Similarity: N.A. 58.9 N.A. 56.5 55.9 59.6
P-Site Identity: N.A. 0 N.A. 0 0 0
P-Site Similarity: N.A. 0 N.A. 20 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 6 0 6 0 0 6 6 12 0 6 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 24 12 0 18 6 18 0 18 12 12 30 6 % D
% Glu: 6 0 12 36 6 0 30 12 0 0 0 0 0 18 0 % E
% Phe: 0 0 0 0 0 6 0 0 0 6 12 0 48 12 6 % F
% Gly: 0 0 6 6 0 12 0 12 0 0 12 12 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % H
% Ile: 0 12 0 0 0 0 12 0 6 0 0 0 18 0 6 % I
% Lys: 0 30 0 6 48 6 0 24 6 36 6 6 0 12 48 % K
% Leu: 53 6 0 0 6 12 0 0 12 12 0 0 0 0 6 % L
% Met: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % M
% Asn: 6 6 12 0 0 36 12 0 30 6 0 24 6 0 0 % N
% Pro: 6 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 6 6 0 0 6 0 0 0 0 0 % Q
% Arg: 0 0 53 0 12 0 0 0 0 0 0 0 0 0 6 % R
% Ser: 6 0 6 6 0 0 0 30 6 0 30 24 0 0 0 % S
% Thr: 6 0 0 6 0 12 6 6 0 6 0 0 0 0 0 % T
% Val: 0 36 0 0 0 0 0 0 6 0 6 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _