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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPME1
All Species:
27.88
Human Site:
T279
Identified Species:
40.89
UniProt:
Q9Y570
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y570
NP_057231.1
386
42315
T279
K
K
E
D
D
M
E
T
K
K
D
H
P
Y
T
Chimpanzee
Pan troglodytes
XP_508638
381
41876
T279
K
K
E
D
D
M
E
T
K
K
D
H
P
Y
T
Rhesus Macaque
Macaca mulatta
XP_001115651
405
44400
T279
K
K
E
D
D
M
E
T
K
K
D
H
P
Y
T
Dog
Lupus familis
XP_850122
386
42276
T279
K
K
E
D
D
M
E
T
K
K
D
H
P
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVQ5
386
42238
T279
K
K
E
D
D
M
E
T
K
K
D
H
P
Y
T
Rat
Rattus norvegicus
XP_341892
386
42298
T279
K
K
E
D
D
M
E
T
K
K
D
H
P
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517056
352
38800
K282
F
L
S
C
P
S
P
K
L
L
L
L
A
G
V
Chicken
Gallus gallus
NP_001026005
359
39669
K289
F
L
S
C
P
T
P
K
L
L
L
L
A
G
V
Frog
Xenopus laevis
NP_001086882
386
42454
T279
K
K
E
D
D
T
D
T
K
K
E
R
P
Y
T
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
L248
S
N
H
L
E
D
I
L
G
F
P
E
F
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648277
409
45331
T302
P
N
T
T
K
S
T
T
E
A
A
K
N
Y
T
Honey Bee
Apis mellifera
XP_623299
384
41915
R281
P
T
G
T
T
A
T
R
K
Y
V
W
R
I
D
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
L287
S
V
P
K
M
L
V
L
A
G
V
D
R
L
D
Sea Urchin
Strong. purpuratus
XP_001202410
365
39617
W285
T
E
H
Y
W
E
G
W
F
K
G
M
S
N
L
Poplar Tree
Populus trichocarpa
XP_002325511
354
39103
L284
P
I
P
K
L
L
L
L
A
G
T
D
R
L
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGG8
454
48937
K379
F
L
E
A
R
G
G
K
M
L
L
L
A
G
T
Conservation
Percent
Protein Identity:
100
98.4
90.3
98.4
N.A.
97.9
97.9
N.A.
86.2
84.7
85.2
20.4
N.A.
47.4
52
42.4
59.5
Protein Similarity:
100
98.6
91.3
98.9
N.A.
99.4
99.4
N.A.
88.5
87.8
93
40.4
N.A.
67.2
70.9
58.8
72.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
0
73.3
6.6
N.A.
20
6.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
0
86.6
13.3
N.A.
26.6
6.6
6.6
13.3
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
N.A.
36.1
Protein Similarity:
60.3
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
0
0
13
7
7
0
19
0
0
% A
% Cys:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
44
44
7
7
0
0
0
38
13
0
7
19
% D
% Glu:
0
7
50
0
7
7
38
0
7
0
7
7
0
0
0
% E
% Phe:
19
0
0
0
0
0
0
0
7
7
0
0
7
0
0
% F
% Gly:
0
0
7
0
0
7
13
0
7
13
7
0
0
19
0
% G
% His:
0
0
13
0
0
0
0
0
0
0
0
38
0
0
0
% H
% Ile:
0
7
0
0
0
0
7
0
0
0
0
0
0
7
0
% I
% Lys:
44
44
0
13
7
0
0
19
50
50
0
7
0
0
0
% K
% Leu:
0
19
0
7
7
13
7
19
13
19
19
19
0
13
7
% L
% Met:
0
0
0
0
7
38
0
0
7
0
0
7
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
0
0
0
7
7
0
% N
% Pro:
19
0
13
0
13
0
13
0
0
0
7
0
44
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
7
0
0
0
7
19
0
0
% R
% Ser:
13
0
13
0
0
13
0
0
0
0
0
0
7
0
0
% S
% Thr:
7
7
7
13
7
13
13
50
0
0
7
0
0
0
63
% T
% Val:
0
7
0
0
0
0
7
0
0
0
13
0
0
0
13
% V
% Trp:
0
0
0
0
7
0
0
7
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
7
0
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _