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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPME1
All Species:
25.15
Human Site:
S243
Identified Species:
36.89
UniProt:
Q9Y570
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y570
NP_057231.1
386
42315
S243
K
Q
C
E
G
I
T
S
P
E
G
S
K
S
I
Chimpanzee
Pan troglodytes
XP_508638
381
41876
S243
K
Q
C
E
G
I
T
S
P
E
G
S
K
S
I
Rhesus Macaque
Macaca mulatta
XP_001115651
405
44400
S243
K
Q
C
E
G
I
T
S
P
E
G
S
K
S
I
Dog
Lupus familis
XP_850122
386
42276
S243
K
Q
C
E
G
I
T
S
P
E
G
S
K
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVQ5
386
42238
S243
K
Q
C
E
G
I
T
S
P
E
G
S
K
S
I
Rat
Rattus norvegicus
XP_341892
386
42298
S243
K
Q
C
E
G
I
T
S
P
E
S
S
K
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517056
352
38800
T243
K
R
K
K
E
D
D
T
E
T
K
K
D
H
P
Chicken
Gallus gallus
NP_001026005
359
39669
T252
K
K
E
D
D
T
E
T
K
K
E
H
L
Y
T
Frog
Xenopus laevis
NP_001086882
386
42454
E243
C
E
E
A
T
T
P
E
G
P
K
A
I
V
E
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
E213
Q
L
R
K
I
V
K
E
R
S
V
R
Q
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648277
409
45331
L243
N
K
L
A
T
N
D
L
P
L
P
D
D
V
L
Honey Bee
Apis mellifera
XP_623299
384
41915
C246
L
L
S
Q
S
S
T
C
Q
C
I
S
E
T
T
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
E251
I
R
E
V
S
E
H
E
Y
T
W
R
I
D
L
Sea Urchin
Strong. purpuratus
XP_001202410
365
39617
Q249
E
S
S
E
S
V
P
Q
S
S
T
Q
A
T
A
Poplar Tree
Populus trichocarpa
XP_002325511
354
39103
C248
K
Y
D
D
S
K
K
C
Y
V
Y
R
T
R
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGG8
454
48937
R328
A
P
V
E
E
L
Q
R
P
E
L
Q
Q
L
P
Conservation
Percent
Protein Identity:
100
98.4
90.3
98.4
N.A.
97.9
97.9
N.A.
86.2
84.7
85.2
20.4
N.A.
47.4
52
42.4
59.5
Protein Similarity:
100
98.6
91.3
98.9
N.A.
99.4
99.4
N.A.
88.5
87.8
93
40.4
N.A.
67.2
70.9
58.8
72.8
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
6.6
6.6
0
0
N.A.
6.6
13.3
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
26.6
33.3
13.3
33.3
N.A.
20
33.3
13.3
26.6
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
N.A.
36.1
Protein Similarity:
60.3
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
13
0
0
0
0
0
0
0
7
7
0
7
% A
% Cys:
7
0
38
0
0
0
0
13
0
7
0
0
0
0
0
% C
% Asp:
0
0
7
13
7
7
13
0
0
0
0
7
13
7
0
% D
% Glu:
7
7
19
50
13
7
7
19
7
44
7
0
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
38
0
0
0
7
0
32
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
7
0
7
0
% H
% Ile:
7
0
0
0
7
38
0
0
0
0
7
0
13
0
38
% I
% Lys:
57
13
7
13
0
7
13
0
7
7
13
7
38
0
0
% K
% Leu:
7
13
7
0
0
7
0
7
0
7
7
0
7
7
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
13
0
50
7
7
0
0
0
13
% P
% Gln:
7
38
0
7
0
0
7
7
7
0
0
13
13
0
0
% Q
% Arg:
0
13
7
0
0
0
0
7
7
0
0
19
0
7
0
% R
% Ser:
0
7
13
0
25
7
0
38
7
13
7
44
0
38
0
% S
% Thr:
0
0
0
0
13
13
44
13
0
13
7
0
7
13
13
% T
% Val:
0
0
7
7
0
13
0
0
0
7
7
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
13
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _