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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM184B
All Species:
27.58
Human Site:
Y108
Identified Species:
55.15
UniProt:
Q9Y519
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y519
NP_036396.2
407
45562
Y108
F
F
T
N
D
Q
Y
Y
V
Y
F
G
T
V
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093431
407
45419
Y108
F
F
T
N
D
Q
Y
Y
V
Y
F
G
T
V
R
Dog
Lupus familis
XP_538375
407
45535
Y108
F
F
T
N
D
Q
Y
Y
V
Y
F
G
T
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG09
407
45570
Y108
F
F
T
N
D
Q
Y
Y
V
Y
F
G
T
V
R
Rat
Rattus norvegicus
Q4QQS1
425
46860
Y120
L
L
G
G
H
P
Y
Y
V
Y
F
D
S
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514054
485
53263
Y184
F
F
T
N
D
Q
Y
Y
V
Y
F
G
T
V
R
Chicken
Gallus gallus
Q5ZMP3
445
50912
V108
Y
P
N
I
A
I
Y
V
D
T
C
R
E
C
Y
Frog
Xenopus laevis
Q6GQE1
444
50312
V108
Y
P
D
I
A
I
Y
V
D
T
C
R
E
C
Y
Zebra Danio
Brachydanio rerio
NP_001017718
387
44077
Y102
F
D
T
V
R
D
C
Y
E
A
F
V
I
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097474
486
53431
Y128
F
F
N
S
D
N
V
Y
I
Y
F
F
T
V
R
Honey Bee
Apis mellifera
XP_392888
417
47458
Y108
F
F
T
V
R
D
C
Y
E
A
F
V
I
Y
N
Nematode Worm
Caenorhab. elegans
NP_510442
398
44523
S108
Y
E
Y
L
G
G
E
S
N
I
M
A
E
I
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.7
98
N.A.
96
59.2
N.A.
76.6
29.8
30.4
81
N.A.
55.1
62.8
57.7
N.A.
Protein Similarity:
100
N.A.
99.2
98.7
N.A.
97
74.3
N.A.
80
46.9
47
86.9
N.A.
65.6
74.8
71.7
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
46.6
N.A.
100
6.6
6.6
26.6
N.A.
60
33.3
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
53.3
N.A.
100
13.3
13.3
26.6
N.A.
73.3
33.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
0
17
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
17
0
0
0
17
0
0
17
0
% C
% Asp:
0
9
9
0
50
17
0
0
17
0
0
9
0
0
0
% D
% Glu:
0
9
0
0
0
0
9
0
17
0
0
0
25
0
0
% E
% Phe:
67
59
0
0
0
0
0
0
0
0
75
9
0
0
0
% F
% Gly:
0
0
9
9
9
9
0
0
0
0
0
42
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
0
17
0
0
9
9
0
0
17
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
17
42
0
9
0
0
9
0
0
0
0
0
17
% N
% Pro:
0
17
0
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
17
0
0
0
0
0
0
17
0
0
67
% R
% Ser:
0
0
0
9
0
0
0
9
0
0
0
0
9
0
0
% S
% Thr:
0
0
59
0
0
0
0
0
0
17
0
0
50
0
0
% T
% Val:
0
0
0
17
0
0
9
17
50
0
0
17
0
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
0
9
0
0
0
67
75
0
59
0
0
0
17
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _