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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARIH1
All Species:
20
Human Site:
Y508
Identified Species:
48.89
UniProt:
Q9Y4X5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4X5
NP_005735.2
557
64118
Y508
A
T
E
V
L
S
G
Y
L
E
R
D
I
S
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1K5
555
63998
Y506
A
T
E
V
L
S
G
Y
L
E
R
D
I
S
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508466
561
64904
Y512
A
T
E
V
L
S
G
Y
L
E
R
D
I
S
Q
Chicken
Gallus gallus
NP_001025558
349
41380
L301
T
E
V
L
S
G
Y
L
E
R
D
I
S
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94981
503
58914
Y455
A
T
E
M
L
S
E
Y
L
E
R
D
I
T
S
Honey Bee
Apis mellifera
XP_396912
509
59268
Y461
T
T
E
R
L
S
E
Y
L
E
R
D
I
T
S
Nematode Worm
Caenorhab. elegans
Q22431
482
55789
F433
A
T
P
R
K
N
L
F
E
Y
Q
Q
A
Q
L
Sea Urchin
Strong. purpuratus
XP_784503
513
60048
Y464
A
T
E
T
L
S
E
Y
L
E
R
D
I
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84RR0
562
63960
C469
G
L
E
R
L
H
Q
C
V
E
K
D
L
V
Q
Baker's Yeast
Sacchar. cerevisiae
P36113
551
63551
E503
N
A
V
E
S
L
S
E
L
L
Q
I
K
T
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
99
N.A.
N.A.
79.3
62.6
N.A.
N.A.
N.A.
62.2
65.7
30.8
65.5
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
99.4
N.A.
N.A.
80.9
62.6
N.A.
N.A.
N.A.
74.5
78.2
50.2
76.3
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
100
0
N.A.
N.A.
N.A.
73.3
66.6
13.3
73.3
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
100
6.6
N.A.
N.A.
N.A.
86.6
73.3
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.8
29.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
48.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
70
0
0
10
% D
% Glu:
0
10
70
10
0
0
30
10
20
70
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
10
30
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
20
60
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
10
0
10
0
0
% K
% Leu:
0
10
0
10
70
10
10
10
70
10
0
0
10
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
20
10
0
20
40
% Q
% Arg:
0
0
0
30
0
0
0
0
0
10
60
0
0
0
0
% R
% Ser:
0
0
0
0
20
60
10
0
0
0
0
0
10
30
30
% S
% Thr:
20
70
0
10
0
0
0
0
0
0
0
0
0
40
0
% T
% Val:
0
0
20
30
0
0
0
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
60
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _