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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AFG3L2
All Species:
46.06
Human Site:
Y756
Identified Species:
77.95
UniProt:
Q9Y4W6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4W6
NP_006787.1
797
88584
Y756
P
F
A
E
K
S
T
Y
E
E
F
V
E
G
T
Chimpanzee
Pan troglodytes
XP_512199
797
88551
Y756
P
F
A
E
K
S
T
Y
E
E
F
V
E
G
T
Rhesus Macaque
Macaca mulatta
XP_001094146
798
88780
Y757
P
F
A
E
K
S
T
Y
E
E
F
V
E
G
T
Dog
Lupus familis
XP_547682
806
89781
Y757
P
F
V
E
K
S
T
Y
E
E
F
V
E
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZQ2
802
89500
Y755
P
F
T
E
K
S
T
Y
E
E
F
V
E
G
T
Rat
Rattus norvegicus
Q7TT47
744
82104
P717
I
G
P
P
P
H
G
P
K
K
M
I
A
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510851
790
87620
Y741
P
F
A
E
K
S
T
Y
E
E
F
V
E
G
T
Chicken
Gallus gallus
XP_419121
806
89372
Y757
P
F
A
E
K
S
T
Y
E
E
F
V
E
G
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001104667
800
88678
Y751
P
F
A
E
K
S
T
Y
E
E
F
V
E
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730248
826
89682
Y774
P
F
K
E
K
S
T
Y
E
E
F
V
E
G
T
Honey Bee
Apis mellifera
XP_624548
803
91087
Y747
P
F
P
E
K
S
T
Y
E
Q
F
V
E
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783782
792
87074
Y749
P
F
A
E
R
T
T
Y
E
D
F
V
E
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZI8
813
89536
Y774
K
S
G
E
T
T
N
Y
D
R
F
K
S
G
F
Baker's Yeast
Sacchar. cerevisiae
P40341
825
93258
A794
P
F
P
E
R
N
D
A
F
D
K
Y
L
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
94.2
N.A.
92.6
36.1
N.A.
72.7
80.8
N.A.
81
N.A.
60.6
61.3
N.A.
63.3
Protein Similarity:
100
100
99.1
95.9
N.A.
95.2
52.7
N.A.
82.4
87.7
N.A.
88.1
N.A.
73
75.2
N.A.
76.7
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
100
100
N.A.
100
N.A.
93.3
86.6
N.A.
80
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
20
N.A.
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61
62.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
0
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
8
15
0
0
0
0
8
% D
% Glu:
0
0
0
93
0
0
0
0
79
65
0
0
79
0
0
% E
% Phe:
0
86
0
0
0
0
0
0
8
0
86
0
0
0
8
% F
% Gly:
0
8
8
0
0
0
8
0
0
0
0
0
0
86
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
8
0
72
0
0
0
8
8
8
8
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
0
0
0
8
0
% N
% Pro:
86
0
22
8
8
0
0
8
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% Q
% Arg:
0
0
0
0
15
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
72
0
0
0
0
0
0
8
0
0
% S
% Thr:
0
0
8
0
8
15
79
0
0
0
0
0
0
0
79
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
79
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
86
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _