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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPEF1
All Species:
17.58
Human Site:
S61
Identified Species:
55.24
UniProt:
Q9Y4P9
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P9
NP_056232.2
236
26987
S61
H
N
Y
V
P
A
N
S
L
Q
Q
K
L
S
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115387
236
26927
S61
H
N
Y
V
P
A
N
S
L
Q
Q
K
L
S
N
Dog
Lupus familis
XP_542915
236
26774
S61
H
N
Y
V
P
A
N
S
L
Q
Q
K
L
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q99JL1
234
26820
S61
H
N
Y
V
P
A
N
S
L
Q
Q
K
L
S
N
Rat
Rattus norvegicus
NP_001034113
157
17997
R27
I
P
L
S
R
P
K
R
N
L
S
R
D
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423842
150
16846
K20
L
L
V
A
E
V
V
K
F
F
F
P
A
M
V
Frog
Xenopus laevis
NP_001090406
229
26222
S61
H
N
Y
V
P
A
N
S
T
T
Q
K
L
S
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782895
253
28565
R72
E
N
W
K
L
L
N
R
K
V
L
T
K
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.7
90.6
N.A.
88.1
60.5
N.A.
N.A.
32.6
57.2
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Protein Similarity:
100
N.A.
97.4
94.4
N.A.
91.9
63.1
N.A.
N.A.
46.1
71.6
N.A.
N.A.
N.A.
N.A.
N.A.
63.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
N.A.
0
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
N.A.
0
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
63
0
0
0
0
0
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% D
% Glu:
13
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
13
13
13
0
0
13
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
63
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
13
0
0
13
13
13
0
0
63
13
0
0
% K
% Leu:
13
13
13
0
13
13
0
0
50
13
13
0
63
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
75
0
0
0
0
75
0
13
0
0
0
0
0
75
% N
% Pro:
0
13
0
0
63
13
0
0
0
0
0
13
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
50
63
0
0
0
0
% Q
% Arg:
0
0
0
0
13
0
0
25
0
0
0
13
0
0
0
% R
% Ser:
0
0
0
13
0
0
0
63
0
0
13
0
0
63
13
% S
% Thr:
0
0
0
0
0
0
0
0
13
13
0
13
0
0
0
% T
% Val:
0
0
13
63
0
13
13
0
0
13
0
0
0
0
13
% V
% Trp:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _