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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPEF1
All Species:
4.55
Human Site:
S160
Identified Species:
14.29
UniProt:
Q9Y4P9
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P9
NP_056232.2
236
26987
S160
P
Q
G
G
G
Q
L
S
W
D
R
P
P
A
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115387
236
26927
S160
P
Q
G
E
G
Q
L
S
G
V
R
P
P
A
P
Dog
Lupus familis
XP_542915
236
26774
R160
P
Q
G
G
G
Q
L
R
E
G
R
L
P
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99JL1
234
26820
R158
P
A
L
G
E
Q
L
R
E
G
R
P
L
A
S
Rat
Rattus norvegicus
NP_001034113
157
17997
S96
M
R
K
I
A
Q
C
S
P
G
V
V
E
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423842
150
16846
E89
L
L
R
Q
K
I
E
E
K
Q
K
L
V
K
A
Frog
Xenopus laevis
NP_001090406
229
26222
A155
E
L
S
P
R
Q
G
A
R
V
D
P
A
S
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782895
253
28565
D178
P
P
H
Q
G
L
S
D
P
R
G
A
S
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.7
90.6
N.A.
88.1
60.5
N.A.
N.A.
32.6
57.2
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Protein Similarity:
100
N.A.
97.4
94.4
N.A.
91.9
63.1
N.A.
N.A.
46.1
71.6
N.A.
N.A.
N.A.
N.A.
N.A.
63.6
P-Site Identity:
100
N.A.
80
66.6
N.A.
46.6
13.3
N.A.
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
80
66.6
N.A.
46.6
20
N.A.
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
13
0
0
13
0
0
0
13
13
38
13
% A
% Cys:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
13
0
13
13
0
0
0
0
% D
% Glu:
13
0
0
13
13
0
13
13
25
0
0
0
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
38
38
50
0
13
0
13
38
13
0
0
13
0
% G
% His:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
0
13
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
13
0
0
0
13
0
13
0
0
13
13
% K
% Leu:
13
25
13
0
0
13
50
0
0
0
0
25
13
13
0
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
63
13
0
13
0
0
0
0
25
0
0
50
38
0
38
% P
% Gln:
0
38
0
25
0
75
0
0
0
13
0
0
0
0
0
% Q
% Arg:
0
13
13
0
13
0
0
25
13
13
50
0
0
0
13
% R
% Ser:
0
0
13
0
0
0
13
38
0
0
0
0
13
13
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
25
13
13
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _