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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WIPI2 All Species: 0.91
Human Site: T415 Identified Species: 1.82
UniProt: Q9Y4P8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4P8 NP_001028690.1 454 49408 T415 T Y V P S S P T R L A Y T D D
Chimpanzee Pan troglodytes XP_001165276 446 48667 R407 S E D G G A L R G E V I P E H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850630 436 47691 R398 H V P S S P T R L A Y G D E L
Cat Felis silvestris
Mouse Mus musculus Q80W47 445 48459 N406 L G K G Q D A N L E A Y T D D
Rat Rattus norvegicus Q6AY57 445 48501 N406 L G K G Q D A N L E A Y T D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512711 416 45669 T379 A A V T K A Y T D D L G A V G
Chicken Gallus gallus Q5ZHN3 436 47757 R398 Y V P S S P T R H A Y T E D L
Frog Xenopus laevis Q7ZWU5 435 47675 H398 P P P S P T R H A Y A D D L G
Zebra Danio Brachydanio rerio Q7ZUW6 344 38148 A307 A F G T E P N A V I A I C A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624581 392 43147 Q355 G D C T L L K Q H R L D G K R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781358 486 52131 D441 P M I P S T V D H R H D E L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q96U88 461 50001 G424 V M V V T S D G G F Y V Y N I
Conservation
Percent
Protein Identity: 100 55 N.A. 91.8 N.A. 93.1 93.6 N.A. 86.5 91.1 85 26.8 N.A. N.A. 61.4 N.A. 63.7
Protein Similarity: 100 72.6 N.A. 93.8 N.A. 94.7 94.9 N.A. 88.5 93.1 90.3 40.5 N.A. N.A. 72 N.A. 73
P-Site Identity: 100 0 N.A. 6.6 N.A. 33.3 33.3 N.A. 13.3 13.3 6.6 13.3 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 20 N.A. 13.3 N.A. 33.3 33.3 N.A. 20 13.3 13.3 26.6 N.A. N.A. 0 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.4
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 45.3
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 0 0 0 17 17 9 9 17 42 0 9 9 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 9 9 0 0 17 9 9 9 9 0 25 17 34 34 % D
% Glu: 0 9 0 0 9 0 0 0 0 25 0 0 17 17 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 9 17 9 25 9 0 0 9 17 0 0 17 9 0 17 % G
% His: 9 0 0 0 0 0 0 9 25 0 9 0 0 0 9 % H
% Ile: 0 0 9 0 0 0 0 0 0 9 0 17 0 0 9 % I
% Lys: 0 0 17 0 9 0 9 0 0 0 0 0 0 9 0 % K
% Leu: 17 0 0 0 9 9 9 0 25 9 17 0 0 17 25 % L
% Met: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 17 0 0 0 0 0 9 0 % N
% Pro: 17 9 25 17 9 25 9 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 0 0 17 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 25 9 17 0 0 0 0 9 % R
% Ser: 9 0 0 25 34 17 0 0 0 0 0 0 0 0 0 % S
% Thr: 9 0 0 25 9 17 17 17 0 0 0 9 25 0 0 % T
% Val: 9 17 25 9 0 0 9 0 9 0 9 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 9 0 0 0 0 9 0 0 9 25 25 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _