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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WIPI2
All Species:
13.64
Human Site:
S436
Identified Species:
27.27
UniProt:
Q9Y4P8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P8
NP_001028690.1
454
49408
S436
A
C
L
E
D
E
A
S
A
L
R
L
D
E
D
Chimpanzee
Pan troglodytes
XP_001165276
446
48667
E428
V
C
L
D
D
E
N
E
F
P
P
I
I
L
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850630
436
47691
S418
A
C
L
E
E
E
A
S
A
L
R
L
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80W47
445
48459
S427
A
C
L
E
D
E
A
S
A
L
R
L
D
E
D
Rat
Rattus norvegicus
Q6AY57
445
48501
S427
A
C
L
E
D
E
A
S
A
L
R
L
D
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512711
416
45669
L399
D
E
T
S
A
L
R
L
D
E
D
N
E
D
N
Chicken
Gallus gallus
Q5ZHN3
436
47757
N418
A
C
L
E
D
E
T
N
S
L
R
L
D
E
D
Frog
Xenopus laevis
Q7ZWU5
435
47675
N418
S
E
E
D
E
M
G
N
L
R
L
D
E
D
N
Zebra Danio
Brachydanio rerio
Q7ZUW6
344
38148
E327
F
L
F
N
P
K
G
E
C
S
R
D
V
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624581
392
43147
L375
A
S
V
S
T
A
G
L
G
S
G
E
P
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781358
486
52131
N468
P
G
I
A
A
G
L
N
Q
L
R
L
D
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q96U88
461
50001
Q444
G
E
G
Y
L
V
K
Q
F
S
V
L
D
G
D
Conservation
Percent
Protein Identity:
100
55
N.A.
91.8
N.A.
93.1
93.6
N.A.
86.5
91.1
85
26.8
N.A.
N.A.
61.4
N.A.
63.7
Protein Similarity:
100
72.6
N.A.
93.8
N.A.
94.7
94.9
N.A.
88.5
93.1
90.3
40.5
N.A.
N.A.
72
N.A.
73
P-Site Identity:
100
26.6
N.A.
86.6
N.A.
100
100
N.A.
0
80
0
6.6
N.A.
N.A.
6.6
N.A.
33.3
P-Site Similarity:
100
40
N.A.
100
N.A.
100
100
N.A.
20
93.3
46.6
13.3
N.A.
N.A.
13.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
45.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
9
17
9
34
0
34
0
0
0
0
0
9
% A
% Cys:
0
50
0
0
0
0
0
0
9
0
0
0
0
0
9
% C
% Asp:
9
0
0
17
42
0
0
0
9
0
9
17
50
25
59
% D
% Glu:
0
25
9
42
17
50
0
17
0
9
0
9
25
42
0
% E
% Phe:
9
0
9
0
0
0
0
0
17
0
0
0
0
0
0
% F
% Gly:
9
9
9
0
0
9
25
0
9
0
9
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
9
9
0
0
% I
% Lys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
50
0
9
9
9
17
9
50
9
59
0
9
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
25
0
0
0
9
0
0
17
% N
% Pro:
9
0
0
0
9
0
0
0
0
9
9
0
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
9
59
0
0
0
0
% R
% Ser:
9
9
0
17
0
0
0
34
9
25
0
0
0
0
9
% S
% Thr:
0
0
9
0
9
0
9
0
0
0
0
0
0
0
0
% T
% Val:
9
0
9
0
0
9
0
0
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _