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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4B
All Species:
36.67
Human Site:
Y265
Identified Species:
62.05
UniProt:
Q9Y4P1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P1
NP_037457.3
393
44309
Y265
G
K
P
N
S
A
H
Y
F
I
G
Y
V
G
E
Chimpanzee
Pan troglodytes
XP_001162556
306
34202
V181
M
M
P
Q
S
L
G
V
I
G
G
K
P
N
S
Rhesus Macaque
Macaca mulatta
XP_001097251
398
45435
Y266
G
K
P
N
N
A
Y
Y
F
I
G
F
L
G
D
Dog
Lupus familis
XP_851977
394
44349
Y266
G
K
P
N
S
A
H
Y
F
I
G
Y
V
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGE6
393
44357
Y265
G
K
P
N
S
A
H
Y
F
I
G
Y
V
G
E
Rat
Rattus norvegicus
NP_001119770
406
45887
Y267
G
K
P
N
N
A
Y
Y
F
I
G
S
L
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513122
528
59425
Y400
G
K
P
N
S
A
H
Y
F
I
G
Y
V
G
G
Chicken
Gallus gallus
Q6PZ02
393
44512
Y265
G
K
P
N
S
A
H
Y
F
I
G
Y
V
G
E
Frog
Xenopus laevis
Q640G7
384
43139
Y256
G
R
P
N
S
A
H
Y
F
I
G
Y
V
G
D
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
Y267
G
K
P
N
S
A
H
Y
F
I
G
F
V
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624577
382
43001
G252
T
H
A
L
Y
F
I
G
C
V
G
N
E
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198708
393
44309
P268
L
G
V
I
G
G
K
P
N
H
A
H
Y
F
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
C287
R
G
G
A
P
I
L
C
I
E
D
A
T
K
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
Y360
I
D
K
I
N
Q
V
Y
E
E
A
L
I
S
T
Conservation
Percent
Protein Identity:
100
74.8
52.5
94.1
N.A.
94.9
52.4
N.A.
65.1
86
73.7
72.8
N.A.
N.A.
49.1
N.A.
49.8
Protein Similarity:
100
75.5
72.6
96.1
N.A.
96.6
70.9
N.A.
70
92.3
87
83.2
N.A.
N.A.
64.8
N.A.
64.3
P-Site Identity:
100
20
66.6
100
N.A.
100
66.6
N.A.
93.3
100
86.6
86.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
20
100
100
N.A.
100
93.3
N.A.
93.3
100
100
100
N.A.
N.A.
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
N.A.
23.5
Protein Similarity:
N.A.
N.A.
N.A.
39.8
N.A.
38.3
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
65
0
0
0
0
15
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
29
% D
% Glu:
0
0
0
0
0
0
0
0
8
15
0
0
8
0
29
% E
% Phe:
0
0
0
0
0
8
0
0
65
0
0
15
0
8
0
% F
% Gly:
65
15
8
0
8
8
8
8
0
8
79
0
0
65
8
% G
% His:
0
8
0
0
0
0
50
0
0
8
0
8
0
0
0
% H
% Ile:
8
0
0
15
0
8
8
0
15
65
0
0
8
0
15
% I
% Lys:
0
58
8
0
0
0
8
0
0
0
0
8
0
8
0
% K
% Leu:
8
0
0
8
0
8
8
0
0
0
0
8
15
0
0
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
65
22
0
0
0
8
0
0
8
0
8
0
% N
% Pro:
0
0
72
0
8
0
0
8
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
58
0
0
0
0
0
0
8
0
8
15
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% T
% Val:
0
0
8
0
0
0
8
8
0
8
0
0
50
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
15
72
0
0
0
43
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _