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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4B
All Species:
31.21
Human Site:
Y239
Identified Species:
52.82
UniProt:
Q9Y4P1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P1
NP_037457.3
393
44309
Y239
L
T
D
I
N
E
A
Y
V
E
T
L
K
H
C
Chimpanzee
Pan troglodytes
XP_001162556
306
34202
R155
L
V
L
L
I
P
L
R
L
G
L
T
D
I
N
Rhesus Macaque
Macaca mulatta
XP_001097251
398
45435
Y240
I
N
Q
I
N
P
V
Y
V
D
A
F
K
E
C
Dog
Lupus familis
XP_851977
394
44349
Y240
L
T
D
I
N
E
A
Y
V
E
T
L
K
R
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGE6
393
44357
Y239
L
T
D
I
N
E
A
Y
V
E
T
L
K
H
C
Rat
Rattus norvegicus
NP_001119770
406
45887
Y241
I
N
Q
I
N
P
V
Y
I
E
A
F
K
E
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513122
528
59425
Y374
L
T
E
I
N
E
A
Y
I
E
T
L
K
H
C
Chicken
Gallus gallus
Q6PZ02
393
44512
Y239
L
T
E
I
N
E
A
Y
I
E
T
L
K
H
C
Frog
Xenopus laevis
Q640G7
384
43139
Y230
L
S
E
I
N
E
A
Y
I
E
T
L
K
H
C
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
Y241
L
S
D
I
N
E
A
Y
I
E
P
L
K
Q
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624577
382
43001
G226
I
N
P
I
Y
I
N
G
L
K
T
S
F
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198708
393
44309
E242
P
L
R
L
G
L
N
E
I
N
T
V
Y
M
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
K261
K
R
K
Q
T
D
S
K
N
Q
T
L
P
M
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
N334
D
S
F
M
A
V
A
N
P
D
G
R
G
F
Q
Conservation
Percent
Protein Identity:
100
74.8
52.5
94.1
N.A.
94.9
52.4
N.A.
65.1
86
73.7
72.8
N.A.
N.A.
49.1
N.A.
49.8
Protein Similarity:
100
75.5
72.6
96.1
N.A.
96.6
70.9
N.A.
70
92.3
87
83.2
N.A.
N.A.
64.8
N.A.
64.3
P-Site Identity:
100
6.6
40
93.3
N.A.
100
40
N.A.
86.6
86.6
80
73.3
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
20
53.3
93.3
N.A.
100
53.3
N.A.
100
100
100
86.6
N.A.
N.A.
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
N.A.
23.5
Protein Similarity:
N.A.
N.A.
N.A.
39.8
N.A.
38.3
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
58
0
0
0
15
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
65
% C
% Asp:
8
0
29
0
0
8
0
0
0
15
0
0
8
0
0
% D
% Glu:
0
0
22
0
0
50
0
8
0
58
0
0
0
15
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
15
8
8
0
% F
% Gly:
0
0
0
0
8
0
0
8
0
8
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
36
0
% H
% Ile:
22
0
0
72
8
8
0
0
43
0
0
0
0
8
8
% I
% Lys:
8
0
8
0
0
0
0
8
0
8
0
0
65
8
0
% K
% Leu:
58
8
8
15
0
8
8
0
15
0
8
58
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
15
0
% M
% Asn:
0
22
0
0
65
0
15
8
8
8
0
0
0
0
8
% N
% Pro:
8
0
8
0
0
22
0
0
8
0
8
0
8
0
0
% P
% Gln:
0
0
15
8
0
0
0
0
0
8
0
0
0
8
15
% Q
% Arg:
0
8
8
0
0
0
0
8
0
0
0
8
0
8
0
% R
% Ser:
0
22
0
0
0
0
8
0
0
0
0
8
0
0
0
% S
% Thr:
0
36
0
0
8
0
0
0
0
0
65
8
0
0
0
% T
% Val:
0
8
0
0
0
8
15
0
29
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
65
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _