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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4B
All Species:
3.94
Human Site:
T185
Identified Species:
6.67
UniProt:
Q9Y4P1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P1
NP_037457.3
393
44309
T185
E
I
R
R
L
C
R
T
S
V
P
C
A
G
A
Chimpanzee
Pan troglodytes
XP_001162556
306
34202
M102
A
M
D
N
T
V
V
M
E
E
I
R
R
L
C
Rhesus Macaque
Macaca mulatta
XP_001097251
398
45435
R187
E
D
I
K
K
M
C
R
V
L
P
L
S
A
D
Dog
Lupus familis
XP_851977
394
44349
G186
D
I
R
R
L
C
R
G
S
L
P
C
A
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGE6
393
44357
A185
E
I
R
R
L
C
R
A
N
L
P
C
A
G
A
Rat
Rattus norvegicus
NP_001119770
406
45887
V188
D
I
K
K
M
C
C
V
L
P
V
G
A
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513122
528
59425
P321
E
I
R
R
L
C
K
P
N
F
P
A
G
A
S
Chicken
Gallus gallus
Q6PZ02
393
44512
S184
E
I
R
R
L
C
Q
S
N
F
S
C
A
G
A
Frog
Xenopus laevis
Q640G7
384
43139
D176
M
D
N
T
V
V
V
D
E
I
R
R
L
C
R
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
P185
E
I
K
R
L
C
M
P
W
L
D
F
D
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624577
382
43001
L172
H
V
A
L
D
N
T
L
I
V
N
D
I
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198708
393
44309
L188
V
I
E
D
I
R
K
L
C
T
V
N
S
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
L207
E
Q
E
Y
L
E
T
L
E
P
F
G
D
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
L274
D
P
R
A
P
Y
S
L
H
N
F
V
K
Y
G
Conservation
Percent
Protein Identity:
100
74.8
52.5
94.1
N.A.
94.9
52.4
N.A.
65.1
86
73.7
72.8
N.A.
N.A.
49.1
N.A.
49.8
Protein Similarity:
100
75.5
72.6
96.1
N.A.
96.6
70.9
N.A.
70
92.3
87
83.2
N.A.
N.A.
64.8
N.A.
64.3
P-Site Identity:
100
0
13.3
80
N.A.
80
20
N.A.
46.6
66.6
0
33.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
6.6
33.3
93.3
N.A.
93.3
46.6
N.A.
66.6
86.6
13.3
46.6
N.A.
N.A.
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
N.A.
23.5
Protein Similarity:
N.A.
N.A.
N.A.
39.8
N.A.
38.3
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
0
0
8
0
0
0
8
36
22
29
% A
% Cys:
0
0
0
0
0
50
15
0
8
0
0
29
0
8
8
% C
% Asp:
22
15
8
8
8
0
0
8
0
0
8
8
15
0
15
% D
% Glu:
50
0
15
0
0
8
0
0
22
8
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
15
15
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
15
8
29
15
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
58
8
0
8
0
0
0
8
8
8
0
8
0
0
% I
% Lys:
0
0
15
15
8
0
15
0
0
0
0
0
8
0
8
% K
% Leu:
0
0
0
8
50
0
0
29
8
29
0
8
8
15
0
% L
% Met:
8
8
0
0
8
8
8
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
8
0
0
22
8
8
8
0
0
0
% N
% Pro:
0
8
0
0
8
0
0
15
0
15
36
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
43
43
0
8
22
8
0
0
8
15
8
8
8
% R
% Ser:
0
0
0
0
0
0
8
8
15
0
8
0
15
8
8
% S
% Thr:
0
0
0
8
8
0
15
8
0
8
0
0
0
8
8
% T
% Val:
8
8
0
0
8
15
15
8
8
15
15
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _