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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYOU1
All Species:
25.15
Human Site:
T575
Identified Species:
42.56
UniProt:
Q9Y4L1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4L1
NP_001124463.1
999
111335
T575
A
E
E
E
S
T
L
T
K
L
G
N
T
I
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096142
916
102146
T492
P
E
E
E
S
T
L
T
K
L
G
N
T
I
S
Dog
Lupus familis
XP_536547
1100
121754
T575
P
E
E
E
S
T
L
T
K
L
G
N
T
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKR6
999
111163
T575
P
E
E
E
S
T
L
T
K
L
G
N
T
I
S
Rat
Rattus norvegicus
Q63617
999
111271
T575
P
E
E
E
S
T
L
T
K
L
G
N
T
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK7
1002
112301
T567
L
E
E
E
S
T
L
T
K
L
G
N
T
I
S
Frog
Xenopus laevis
Q566I3
646
72655
A293
D
V
R
E
N
Q
R
A
M
N
K
L
L
K
E
Zebra Danio
Brachydanio rerio
Q7ZUW2
980
110301
K565
E
E
E
S
T
L
T
K
L
G
N
T
I
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INI8
641
70177
G288
E
I
D
A
L
F
E
G
Q
D
F
Y
T
K
V
Honey Bee
Apis mellifera
XP_624153
932
105575
S560
D
E
E
E
S
T
F
S
I
L
G
S
T
I
S
Nematode Worm
Caenorhab. elegans
P09446
640
69704
S287
Q
A
S
I
E
I
D
S
L
F
E
G
I
D
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002322555
881
98313
K516
G
L
A
D
A
S
E
K
Y
S
S
R
N
L
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567510
867
96706
A510
S
V
S
G
L
A
D
A
S
E
K
Y
S
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
O74225
707
78655
A354
S
V
K
E
R
I
Q
A
F
F
G
K
Q
L
S
Conservation
Percent
Protein Identity:
100
N.A.
89
83.3
N.A.
92
91.6
N.A.
N.A.
69.1
49.3
65.3
N.A.
24.5
42.4
24.6
N.A.
Protein Similarity:
100
N.A.
90
86
N.A.
95.5
94.7
N.A.
N.A.
80.7
56.4
77.4
N.A.
38.7
60
39.5
N.A.
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
6.6
20
N.A.
6.6
66.6
0
N.A.
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
13.3
26.6
N.A.
20
80
6.6
N.A.
Percent
Protein Identity:
29.7
N.A.
N.A.
30.7
N.A.
26.5
Protein Similarity:
50.7
N.A.
N.A.
49
N.A.
43.1
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
33.3
N.A.
N.A.
13.3
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
8
8
0
22
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
8
8
0
0
15
0
0
8
0
0
0
8
0
% D
% Glu:
15
58
58
65
8
0
15
0
0
8
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
8
8
0
8
15
8
0
0
0
8
% F
% Gly:
8
0
0
8
0
0
0
8
0
8
58
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
15
0
0
8
0
0
0
15
50
0
% I
% Lys:
0
0
8
0
0
0
0
15
43
0
15
8
0
15
0
% K
% Leu:
8
8
0
0
15
8
43
0
15
50
0
8
8
15
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
8
8
43
8
0
0
% N
% Pro:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
8
8
0
8
0
0
0
8
0
0
% Q
% Arg:
0
0
8
0
8
0
8
0
0
0
0
8
0
0
8
% R
% Ser:
15
0
15
8
50
8
0
15
8
8
8
8
8
15
72
% S
% Thr:
0
0
0
0
8
50
8
43
0
0
0
8
58
0
0
% T
% Val:
0
22
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _