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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRAF6 All Species: 31.52
Human Site: Y418 Identified Species: 69.33
UniProt: Q9Y4K3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4K3 NP_004611.1 522 59573 Y418 V H T M Q G E Y D S H L P W P
Chimpanzee Pan troglodytes XP_001154065 522 59541 Y418 V H T M Q G E Y D S H L P W P
Rhesus Macaque Macaca mulatta B6CJY5 522 59446 Y418 V H T M Q G E Y D S H L P W P
Dog Lupus familis XP_857114 509 56866 I402 G Y K M C L R I Y L N G D G T
Cat Felis silvestris
Mouse Mus musculus P70196 530 60051 Y426 V H T M Q G E Y D S H L P W P
Rat Rattus norvegicus B5DF45 530 60235 Y426 V H T M Q G E Y D S H L P W P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509071 544 61760 Y440 V H T M Q G E Y D S H L P W P
Chicken Gallus gallus XP_421089 524 59597 Y420 V H T M Q G E Y D S H L P W P
Frog Xenopus laevis Q3MV19 556 63019 Y452 V H T M Q G D Y D S L L P W P
Zebra Danio Brachydanio rerio Q6IWL4 542 61788 F442 V H T M Q G E F D S Q L S W P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789994 462 53330 F365 K V L Y I S L F V H F M Q G K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98 27.5 N.A. 88.4 87.1 N.A. 81.8 76.1 62.9 57 N.A. N.A. N.A. N.A. 24.3
Protein Similarity: 100 99.8 99.4 45.9 N.A. 93 91.8 N.A. 88.2 86.2 74.4 70.8 N.A. N.A. N.A. N.A. 41
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 100 100 86.6 80 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. 100 100 93.3 86.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 82 0 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 73 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 19 0 0 10 0 0 0 0 % F
% Gly: 10 0 0 0 0 82 0 0 0 0 0 10 0 19 0 % G
% His: 0 82 0 0 0 0 0 0 0 10 64 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 10 0 0 10 10 0 0 10 10 82 0 0 0 % L
% Met: 0 0 0 91 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 73 0 82 % P
% Gln: 0 0 0 0 82 0 0 0 0 0 10 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 0 0 0 82 0 0 10 0 0 % S
% Thr: 0 0 82 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 82 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 82 0 % W
% Tyr: 0 10 0 10 0 0 0 73 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _