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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAF6
All Species:
26.36
Human Site:
S188
Identified Species:
58
UniProt:
Q9Y4K3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4K3
NP_004611.1
522
59573
S188
D
C
P
R
R
Q
V
S
C
D
N
C
A
A
S
Chimpanzee
Pan troglodytes
XP_001154065
522
59541
S188
D
C
P
R
R
Q
V
S
C
D
N
C
A
A
S
Rhesus Macaque
Macaca mulatta
B6CJY5
522
59446
S188
D
C
P
R
R
Q
V
S
C
D
N
C
A
A
L
Dog
Lupus familis
XP_857114
509
56866
S162
E
C
P
E
R
S
L
S
C
R
H
C
R
A
P
Cat
Felis silvestris
Mouse
Mus musculus
P70196
530
60051
S188
D
C
P
R
R
Q
V
S
C
V
N
C
A
V
S
Rat
Rattus norvegicus
B5DF45
530
60235
S188
D
C
P
R
R
Q
V
S
C
V
N
C
A
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509071
544
61760
S188
E
C
P
R
R
Q
V
S
C
V
N
C
A
L
S
Chicken
Gallus gallus
XP_421089
524
59597
C188
E
C
P
R
R
Q
V
C
C
P
N
C
A
T
S
Frog
Xenopus laevis
Q3MV19
556
63019
F190
E
C
G
R
R
R
T
F
C
D
N
C
G
L
A
Zebra Danio
Brachydanio rerio
Q6IWL4
542
61788
T189
H
C
L
Q
R
I
M
T
C
P
D
C
A
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789994
462
53330
E152
I
H
V
S
Q
S
M
E
A
H
L
Q
L
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98
27.5
N.A.
88.4
87.1
N.A.
81.8
76.1
62.9
57
N.A.
N.A.
N.A.
N.A.
24.3
Protein Similarity:
100
99.8
99.4
45.9
N.A.
93
91.8
N.A.
88.2
86.2
74.4
70.8
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
100
100
93.3
46.6
N.A.
86.6
80
N.A.
80
73.3
46.6
40
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
66.6
N.A.
86.6
80
N.A.
86.6
80
66.6
66.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
73
37
19
% A
% Cys:
0
91
0
0
0
0
0
10
91
0
0
91
0
0
0
% C
% Asp:
46
0
0
0
0
0
0
0
0
37
10
0
0
0
0
% D
% Glu:
37
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% G
% His:
10
10
0
0
0
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
10
0
0
0
10
0
10
19
10
% L
% Met:
0
0
0
0
0
0
19
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
73
0
0
0
0
% N
% Pro:
0
0
73
0
0
0
0
0
0
19
0
0
0
0
19
% P
% Gln:
0
0
0
10
10
64
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
73
91
10
0
0
0
10
0
0
10
0
0
% R
% Ser:
0
0
0
10
0
19
0
64
0
0
0
0
0
0
55
% S
% Thr:
0
0
0
0
0
0
10
10
0
0
0
0
0
10
0
% T
% Val:
0
0
10
0
0
0
64
0
0
28
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _