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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LOXL2
All Species:
19.09
Human Site:
Y444
Identified Species:
42
UniProt:
Q9Y4K0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4K0
NP_002309.1
774
86725
Y444
L
N
G
G
R
N
P
Y
E
G
R
V
E
V
L
Chimpanzee
Pan troglodytes
Q5G271
875
97141
K509
L
V
D
G
E
N
K
K
E
G
R
V
E
V
F
Rhesus Macaque
Macaca mulatta
Q5G267
875
97168
K509
L
M
D
G
E
N
K
K
E
G
R
V
E
V
F
Dog
Lupus familis
XP_543244
854
94603
Y444
L
N
G
G
R
N
P
Y
E
G
R
V
E
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P58022
776
86985
Y447
L
N
G
G
R
N
P
Y
E
G
R
V
E
V
L
Rat
Rattus norvegicus
P16636
411
46540
R110
P
S
G
V
A
A
G
R
P
R
P
A
A
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506936
887
98469
Y508
L
S
G
G
R
N
P
Y
E
G
R
V
Q
V
L
Chicken
Gallus gallus
Q05063
420
48134
W119
Q
P
L
G
R
R
H
W
F
Q
A
G
Y
R
A
Frog
Xenopus laevis
NP_001121257
765
85638
T435
L
S
G
G
R
H
P
T
E
G
R
V
E
V
L
Zebra Danio
Brachydanio rerio
Q24JV9
567
64113
D266
F
T
A
L
I
P
E
D
N
T
F
Q
T
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P16264
532
57801
T231
E
G
T
E
A
H
I
T
E
C
N
M
P
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.3
20.3
83.4
N.A.
86.2
23.6
N.A.
73
24.2
73.2
20.4
N.A.
N.A.
N.A.
N.A.
23.1
Protein Similarity:
100
35
34.1
87.8
N.A.
92.7
35.7
N.A.
80.7
34.6
84.8
39.5
N.A.
N.A.
N.A.
N.A.
34.7
P-Site Identity:
100
60
60
100
N.A.
100
6.6
N.A.
86.6
13.3
80
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
60
60
100
N.A.
100
13.3
N.A.
100
20
93.3
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
19
10
0
0
0
0
10
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
10
19
0
10
0
73
0
0
0
55
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
10
0
0
0
19
% F
% Gly:
0
10
55
73
0
0
10
0
0
64
0
10
0
0
0
% G
% His:
0
0
0
0
0
19
10
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
19
19
0
0
0
0
0
0
0
% K
% Leu:
64
0
10
10
0
0
0
0
0
0
0
0
0
0
46
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
28
0
0
0
55
0
0
10
0
10
0
0
0
0
% N
% Pro:
10
10
0
0
0
10
46
0
10
0
10
0
10
10
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% Q
% Arg:
0
0
0
0
55
10
0
10
0
10
64
0
0
19
0
% R
% Ser:
0
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
10
10
0
0
0
0
19
0
10
0
0
10
0
10
% T
% Val:
0
10
0
10
0
0
0
0
0
0
0
64
0
73
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _