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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LOXL2 All Species: 20
Human Site: T646 Identified Species: 44
UniProt: Q9Y4K0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4K0 NP_002309.1 774 86725 T646 D L L N L N G T K V A E G H K
Chimpanzee Pan troglodytes Q5G271 875 97141 L732 Y D I A L V R L Q G P E E Q C
Rhesus Macaque Macaca mulatta Q5G267 875 97168 L732 Y D I A L V R L Q G P E E Q C
Dog Lupus familis XP_543244 854 94603 T646 D L L N L N G T K V A E G H K
Cat Felis silvestris
Mouse Mus musculus P58022 776 86985 T648 D L L S L N G T K V A E G H K
Rat Rattus norvegicus P16636 411 46540 S284 R Y S W E W H S C H Q H Y H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506936 887 98469 T710 D L L N L N G T K V A E G H K
Chicken Gallus gallus Q05063 420 48134 S293 R Y S W E W H S C H Q H Y H S
Frog Xenopus laevis NP_001121257 765 85638 T637 D L L T L N G T K V A E G H K
Zebra Danio Brachydanio rerio Q24JV9 567 64113 Y440 D T T V S S P Y Y N Y N Y Y G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P16264 532 57801 V405 L G N G W G R V C D P D W S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.3 20.3 83.4 N.A. 86.2 23.6 N.A. 73 24.2 73.2 20.4 N.A. N.A. N.A. N.A. 23.1
Protein Similarity: 100 35 34.1 87.8 N.A. 92.7 35.7 N.A. 80.7 34.6 84.8 39.5 N.A. N.A. N.A. N.A. 34.7
P-Site Identity: 100 13.3 13.3 100 N.A. 93.3 6.6 N.A. 100 6.6 93.3 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 26.6 26.6 100 N.A. 100 13.3 N.A. 100 13.3 93.3 20 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 0 0 0 0 0 0 46 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 28 0 0 0 0 0 19 % C
% Asp: 55 19 0 0 0 0 0 0 0 10 0 10 0 0 10 % D
% Glu: 0 0 0 0 19 0 0 0 0 0 0 64 19 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 10 0 10 46 0 0 19 0 0 46 0 10 % G
% His: 0 0 0 0 0 0 19 0 0 19 0 19 0 64 0 % H
% Ile: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 46 0 0 0 0 0 46 % K
% Leu: 10 46 46 0 64 0 0 19 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 28 0 46 0 0 0 10 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 0 0 28 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 19 0 19 0 0 19 0 % Q
% Arg: 19 0 0 0 0 0 28 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 19 10 10 10 0 19 0 0 0 0 0 10 19 % S
% Thr: 0 10 10 10 0 0 0 46 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 19 0 10 0 46 0 0 0 0 0 % V
% Trp: 0 0 0 19 10 19 0 0 0 0 0 0 10 0 0 % W
% Tyr: 19 19 0 0 0 0 0 10 10 0 10 0 28 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _