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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LKAP
All Species:
25.76
Human Site:
T246
Identified Species:
70.83
UniProt:
Q9Y4F3
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4F3
NP_055462.2
1741
192728
T246
H
I
S
Q
S
E
L
T
P
H
L
C
T
N
S
Chimpanzee
Pan troglodytes
XP_001149081
1742
192855
T247
H
I
S
Q
S
E
L
T
P
H
L
C
T
N
S
Rhesus Macaque
Macaca mulatta
XP_001108939
1742
192640
T247
H
I
S
Q
S
E
L
T
P
H
L
C
T
N
S
Dog
Lupus familis
XP_863003
1739
191773
T248
H
I
S
Q
S
E
L
T
P
H
L
C
T
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ34
1730
192015
T246
R
L
S
H
S
E
L
T
P
H
L
C
T
N
S
Rat
Rattus norvegicus
Q8VIG2
1735
192657
T246
H
L
S
H
S
E
L
T
P
H
L
C
T
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517167
1744
192618
T247
H
V
A
Q
S
D
L
T
S
H
V
C
T
N
P
Chicken
Gallus gallus
XP_414895
1741
193339
P247
T
S
H
V
C
A
S
P
L
H
L
S
V
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662277
1296
142871
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
93.1
N.A.
85.8
85.3
N.A.
79.3
78.8
N.A.
48.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
99
95.8
N.A.
91.6
90.9
N.A.
87.7
87.8
N.A.
58.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
86.6
N.A.
60
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
86.6
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
12
0
0
0
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
78
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
67
0
12
23
0
0
0
0
0
89
0
0
0
0
0
% H
% Ile:
0
45
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
23
0
0
0
0
78
0
12
0
78
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
78
0
% N
% Pro:
0
0
0
0
0
0
0
12
67
0
0
0
0
0
23
% P
% Gln:
0
0
0
56
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
67
0
78
0
12
0
12
0
0
12
0
0
67
% S
% Thr:
12
0
0
0
0
0
0
78
0
0
0
0
78
0
0
% T
% Val:
0
12
0
12
0
0
0
0
0
0
12
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _