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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V0A2
All Species:
16.36
Human Site:
Y274
Identified Species:
30
UniProt:
Q9Y487
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y487
NP_036595.2
856
98082
Y274
N
T
R
I
Q
D
L
Y
T
V
L
H
K
T
E
Chimpanzee
Pan troglodytes
XP_001165034
837
96375
Q269
N
T
R
I
D
D
L
Q
M
V
L
N
Q
T
E
Rhesus Macaque
Macaca mulatta
XP_001098750
804
92087
R246
A
A
E
S
V
Y
S
R
V
I
Q
V
K
K
M
Dog
Lupus familis
XP_543370
854
97888
Y274
N
T
R
I
Q
D
L
Y
T
V
L
H
K
T
E
Cat
Felis silvestris
Mouse
Mus musculus
P15920
856
98127
Y274
N
T
R
I
Q
D
L
Y
T
V
L
H
K
T
E
Rat
Rattus norvegicus
P25286
838
96309
Q269
N
T
R
I
D
D
L
Q
M
V
L
N
Q
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507655
845
96915
Y262
N
T
R
I
Q
D
L
Y
T
V
L
H
K
T
E
Chicken
Gallus gallus
Q9I8D0
838
95966
Q269
N
T
R
I
D
D
L
Q
M
V
L
N
Q
T
E
Frog
Xenopus laevis
Q8AVM5
831
95538
Q269
N
T
R
I
E
D
L
Q
M
V
L
N
Q
T
E
Zebra Danio
Brachydanio rerio
NP_001116219
849
97474
H277
R
T
R
I
Q
D
L
H
T
V
L
H
R
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30628
905
103383
K305
M
T
R
I
E
D
L
K
T
V
L
G
Q
T
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32563
840
95510
Y285
N
K
N
L
S
D
L
Y
T
V
L
K
T
T
S
Red Bread Mold
Neurospora crassa
Q01290
856
97974
Q290
N
A
R
L
E
D
V
Q
N
V
L
R
N
T
Q
Conservation
Percent
Protein Identity:
100
53.1
92
94.7
N.A.
91.5
53.1
N.A.
78.5
52.7
52.5
68.3
N.A.
N.A.
N.A.
44.4
N.A.
Protein Similarity:
100
70.7
92.9
97.5
N.A.
96.2
70.9
N.A.
86.6
70.2
70.5
81.1
N.A.
N.A.
N.A.
62.9
N.A.
P-Site Identity:
100
66.6
6.6
100
N.A.
100
66.6
N.A.
100
66.6
66.6
80
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
100
80
13.3
100
N.A.
100
80
N.A.
100
80
86.6
93.3
N.A.
N.A.
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37
40.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.7
60.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
24
93
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
24
0
0
0
0
0
0
0
0
0
70
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
39
0
0
0
% H
% Ile:
0
0
0
77
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
8
0
0
0
8
39
8
0
% K
% Leu:
0
0
0
16
0
0
85
0
0
0
93
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
31
0
0
0
0
0
8
% M
% Asn:
77
0
8
0
0
0
0
0
8
0
0
31
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
39
0
0
39
0
0
8
0
39
0
16
% Q
% Arg:
8
0
85
0
0
0
0
8
0
0
0
8
8
0
0
% R
% Ser:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
8
% S
% Thr:
0
77
0
0
0
0
0
0
54
0
0
0
8
93
0
% T
% Val:
0
0
0
0
8
0
8
0
8
93
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _