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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DMXL1
All Species:
20.61
Human Site:
S2562
Identified Species:
50.37
UniProt:
Q9Y485
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y485
NP_005500.4
3027
337853
S2562
H
T
A
E
E
S
L
S
A
G
P
A
I
L
R
Chimpanzee
Pan troglodytes
XP_517890
3022
337411
S2557
H
T
A
E
E
S
L
S
A
G
P
A
I
L
R
Rhesus Macaque
Macaca mulatta
XP_001087241
3025
337728
S2560
H
T
S
E
E
S
L
S
A
G
P
A
I
L
R
Dog
Lupus familis
XP_531861
3029
338250
S2564
H
T
S
E
E
S
L
S
A
G
P
A
I
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PNC0
3013
335990
S2548
H
T
S
E
E
N
V
S
A
G
P
A
I
L
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507192
2864
318995
K2407
P
S
S
K
M
S
S
K
E
C
L
L
E
T
P
Chicken
Gallus gallus
XP_424958
2833
314679
Y2376
S
V
K
R
L
W
Q
Y
L
V
K
Q
E
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665441
3003
332749
T2544
N
Y
I
N
T
Y
P
T
D
L
S
A
G
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510431
2948
330673
Q2486
Q
Q
L
H
R
V
K
Q
F
L
I
L
V
G
F
Sea Urchin
Strong. purpuratus
XP_790747
3216
355082
S2753
F
L
S
E
T
G
G
S
S
M
T
G
L
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.3
94
N.A.
89.6
N.A.
N.A.
78.3
71.5
N.A.
54.6
N.A.
N.A.
N.A.
32.5
38.7
Protein Similarity:
100
99.5
99
97.2
N.A.
94.9
N.A.
N.A.
85.5
81.3
N.A.
70.1
N.A.
N.A.
N.A.
52
57.3
P-Site Identity:
100
100
93.3
93.3
N.A.
80
N.A.
N.A.
6.6
0
N.A.
6.6
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
26.6
0
N.A.
20
N.A.
N.A.
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
0
0
0
50
0
0
60
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
60
50
0
0
0
10
0
0
0
20
10
0
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
10
10
0
0
50
0
10
10
20
20
% G
% His:
50
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
10
0
50
0
0
% I
% Lys:
0
0
10
10
0
0
10
10
0
0
10
0
0
0
0
% K
% Leu:
0
10
10
0
10
0
40
0
10
20
10
20
10
50
0
% L
% Met:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
10
0
0
0
50
0
0
0
10
% P
% Gln:
10
10
0
0
0
0
10
10
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
50
% R
% Ser:
10
10
50
0
0
50
10
60
10
0
10
0
0
10
0
% S
% Thr:
0
50
0
0
20
0
0
10
0
0
10
0
0
10
0
% T
% Val:
0
10
0
0
0
10
10
0
0
10
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _