KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DMXL1
All Species:
17.88
Human Site:
S2217
Identified Species:
43.7
UniProt:
Q9Y485
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y485
NP_005500.4
3027
337853
S2217
H
A
I
I
N
F
D
S
P
P
H
P
D
I
Q
Chimpanzee
Pan troglodytes
XP_517890
3022
337411
S2213
H
A
I
I
N
F
D
S
P
P
H
P
D
I
Q
Rhesus Macaque
Macaca mulatta
XP_001087241
3025
337728
S2217
H
A
I
I
N
F
D
S
P
P
H
P
D
I
Q
Dog
Lupus familis
XP_531861
3029
338250
S2219
H
A
I
I
N
F
D
S
P
P
H
P
D
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6PNC0
3013
335990
S2211
H
A
I
I
N
F
D
S
P
P
H
P
D
S
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507192
2864
318995
E2072
L
Y
H
W
L
E
K
E
V
V
A
L
Q
K
T
Chicken
Gallus gallus
XP_424958
2833
314679
L2041
I
L
H
A
I
I
N
L
D
S
P
F
Y
Y
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665441
3003
332749
L2202
R
N
H
I
H
D
I
L
F
T
I
V
Q
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510431
2948
330673
L2150
V
L
M
E
L
L
L
L
L
L
N
V
Q
R
D
Sea Urchin
Strong. purpuratus
XP_790747
3216
355082
A2381
R
T
V
L
D
F
S
A
P
P
S
P
N
H
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.3
94
N.A.
89.6
N.A.
N.A.
78.3
71.5
N.A.
54.6
N.A.
N.A.
N.A.
32.5
38.7
Protein Similarity:
100
99.5
99
97.2
N.A.
94.9
N.A.
N.A.
85.5
81.3
N.A.
70.1
N.A.
N.A.
N.A.
52
57.3
P-Site Identity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
0
26.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
0
6.6
N.A.
26.6
N.A.
N.A.
N.A.
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
10
0
0
0
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
10
50
0
10
0
0
0
50
0
10
% D
% Glu:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
60
0
0
10
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
50
0
30
0
10
0
0
0
0
0
50
0
0
10
10
% H
% Ile:
10
0
50
60
10
10
10
0
0
0
10
0
0
40
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% K
% Leu:
10
20
0
10
20
10
10
30
10
10
0
10
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
0
0
50
0
10
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
60
60
10
60
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
50
% Q
% Arg:
20
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
10
50
0
10
10
0
0
10
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
10
% T
% Val:
10
0
10
0
0
0
0
0
10
10
0
20
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _