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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAB1
All Species:
25.76
Human Site:
S40
Identified Species:
40.48
UniProt:
Q9Y478
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y478
NP_006244.2
270
30382
S40
R
P
K
I
L
M
D
S
P
E
D
A
D
L
F
Chimpanzee
Pan troglodytes
XP_513749
272
30341
T40
H
K
I
M
V
G
S
T
D
D
P
N
V
F
S
Rhesus Macaque
Macaca mulatta
XP_001093423
272
30312
T40
H
K
I
M
V
G
S
T
D
D
P
S
V
F
S
Dog
Lupus familis
XP_543421
270
30281
S40
R
P
K
I
L
M
D
S
P
E
D
A
D
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9R078
270
30290
S40
R
P
K
I
L
M
D
S
P
E
D
A
D
I
F
Rat
Rattus norvegicus
P80386
270
30376
S40
R
P
K
I
L
M
D
S
P
E
D
A
D
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514296
285
32181
Q55
G
G
A
L
L
V
I
Q
S
P
L
R
S
L
F
Chicken
Gallus gallus
NP_001035001
273
30440
S42
R
P
K
I
L
M
D
S
P
E
D
A
D
L
F
Frog
Xenopus laevis
NP_001085572
266
29829
A51
V
G
E
S
K
G
S
A
E
K
D
E
F
L
A
Zebra Danio
Brachydanio rerio
NP_001002632
268
30343
A40
L
M
D
S
P
E
D
A
D
I
F
H
G
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610460
341
36399
T116
D
D
A
T
S
A
V
T
R
D
H
S
S
M
D
Honey Bee
Apis mellifera
XP_393160
283
31818
S54
S
Q
K
L
V
F
Q
S
S
H
E
E
E
E
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797535
279
30846
A40
K
I
P
I
I
Q
Q
A
S
L
D
D
S
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCY5
289
31974
R74
V
P
V
L
P
L
Q
R
P
D
E
I
H
I
P
Baker's Yeast
Sacchar. cerevisiae
P34164
415
46386
S45
P
Q
E
M
D
A
V
S
K
K
V
T
E
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.5
70.9
98.5
N.A.
96.6
96.3
N.A.
63.8
91.2
80.3
81.1
N.A.
43.9
50.1
N.A.
49.4
Protein Similarity:
100
82.3
82.3
98.8
N.A.
97.7
98.5
N.A.
71.9
94.8
87.7
89.6
N.A.
54.8
66
N.A.
65.2
P-Site Identity:
100
0
0
100
N.A.
93.3
93.3
N.A.
20
100
13.3
6.6
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
26.6
33.3
100
N.A.
100
100
N.A.
33.3
100
33.3
13.3
N.A.
26.6
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.8
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.7
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
0
14
0
20
0
0
0
34
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
0
7
0
40
0
20
27
47
7
34
0
20
% D
% Glu:
0
0
14
0
0
7
0
0
7
34
14
14
14
14
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
7
0
7
14
40
% F
% Gly:
7
14
0
0
0
20
0
0
0
0
0
0
7
0
0
% G
% His:
14
0
0
0
0
0
0
0
0
7
7
7
7
0
0
% H
% Ile:
0
7
14
40
7
0
7
0
0
7
0
7
0
27
0
% I
% Lys:
7
14
40
0
7
0
0
0
7
14
0
0
0
0
0
% K
% Leu:
7
0
0
20
40
7
0
0
0
7
7
0
0
40
0
% L
% Met:
0
7
0
20
0
34
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
7
40
7
0
14
0
0
0
40
7
14
0
0
0
14
% P
% Gln:
0
14
0
0
0
7
20
7
0
0
0
0
0
0
0
% Q
% Arg:
34
0
0
0
0
0
0
7
7
0
0
7
0
0
0
% R
% Ser:
7
0
0
14
7
0
20
47
20
0
0
14
20
0
20
% S
% Thr:
0
0
0
7
0
0
0
20
0
0
0
7
0
0
0
% T
% Val:
14
0
7
0
20
7
14
0
0
0
7
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _